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Instillation of Ophthalmic Formulation Containing Nilvadipine Nanocrystals Attenuates Lens Opacification in Shumiya Cataract Rats

We developed ophthalmic formulations based on nilvadipine (NIL) nanocrystals (NIL-NP dispersions; mean particle size: 98 nm) by using bead mill treatment and investigated whether the instillation of NIL-NP dispersions delivers NIL to the lens and prevents lens opacification in hereditary cataractous...

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Detalles Bibliográficos
Autores principales:	Goto, Ryoka, Yamada, Shigehiro, Otake, Hiroko, Nakazawa, Yosuke, Oka, Mikako, Yamamoto, Naoki, Sasaki, Hiroshi, Nagai, Noriaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709220/ https://www.ncbi.nlm.nih.gov/pubmed/34959281 http://dx.doi.org/10.3390/pharmaceutics13121999

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