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Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review
The coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. This review was und...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709261/ https://www.ncbi.nlm.nih.gov/pubmed/34960150 http://dx.doi.org/10.3390/vaccines9121404 |
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author | Lee, Yu-Kuei Huang, Yi-Hsun |
author_facet | Lee, Yu-Kuei Huang, Yi-Hsun |
author_sort | Lee, Yu-Kuei |
collection | PubMed |
description | The coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. This review was undertaken to help clinicians recognize the possible manifestations and systemic pathogenesis, especially those related to the eye, after receiving COVID-19 vaccination. A systemic search was performed on 22 August 2021 through Embase, Medline, and Cochrane Library for publications on ocular manifestations after COVID-19 vaccination. Two case-control studies/retrospective cohort studies, one cross-sectional study, three case series, sixteen case reports, two images, and seven letters were included. Ocular manifestations after receiving COVID-19 vaccines may appear on the eyelid, cornea and ocular surface, retina, uvea, nerve, and vessel. The ocular manifestations occurred up to forty-two days after vaccination, and vaccine-induced immunologic responses may be responsible. Although the incidence rate of ocular symptoms is considerably lower in the vaccinated subjects than in COVID-19 patients, physicians should be aware of the possible associations between COVID-19 vaccines and ocular symptoms for the early diagnosis and treatment of vision problems or life-threatening complications. |
format | Online Article Text |
id | pubmed-8709261 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87092612021-12-25 Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review Lee, Yu-Kuei Huang, Yi-Hsun Vaccines (Basel) Review The coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. This review was undertaken to help clinicians recognize the possible manifestations and systemic pathogenesis, especially those related to the eye, after receiving COVID-19 vaccination. A systemic search was performed on 22 August 2021 through Embase, Medline, and Cochrane Library for publications on ocular manifestations after COVID-19 vaccination. Two case-control studies/retrospective cohort studies, one cross-sectional study, three case series, sixteen case reports, two images, and seven letters were included. Ocular manifestations after receiving COVID-19 vaccines may appear on the eyelid, cornea and ocular surface, retina, uvea, nerve, and vessel. The ocular manifestations occurred up to forty-two days after vaccination, and vaccine-induced immunologic responses may be responsible. Although the incidence rate of ocular symptoms is considerably lower in the vaccinated subjects than in COVID-19 patients, physicians should be aware of the possible associations between COVID-19 vaccines and ocular symptoms for the early diagnosis and treatment of vision problems or life-threatening complications. MDPI 2021-11-27 /pmc/articles/PMC8709261/ /pubmed/34960150 http://dx.doi.org/10.3390/vaccines9121404 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Lee, Yu-Kuei Huang, Yi-Hsun Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
title | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
title_full | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
title_fullStr | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
title_full_unstemmed | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
title_short | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
title_sort | ocular manifestations after receiving covid-19 vaccine: a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709261/ https://www.ncbi.nlm.nih.gov/pubmed/34960150 http://dx.doi.org/10.3390/vaccines9121404 |
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