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Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease

Despite the increasing array of medications available for the treatment of Crohn’s disease and a focus on mucosal healing, approximately 35% of patients with Crohn’s disease undergo bowel surgery at some stage. The importance of nutritional optimisation before Crohn’s surgery is well-highlighted by...

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Autores principales: Shariff, Sharafaath, Moran, Gordon, Grimes, Caris, Cooney, Rachel Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709272/
https://www.ncbi.nlm.nih.gov/pubmed/34959941
http://dx.doi.org/10.3390/nu13124389
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author Shariff, Sharafaath
Moran, Gordon
Grimes, Caris
Cooney, Rachel Margaret
author_facet Shariff, Sharafaath
Moran, Gordon
Grimes, Caris
Cooney, Rachel Margaret
author_sort Shariff, Sharafaath
collection PubMed
description Despite the increasing array of medications available for the treatment of Crohn’s disease and a focus on mucosal healing, approximately 35% of patients with Crohn’s disease undergo bowel surgery at some stage. The importance of nutritional optimisation before Crohn’s surgery is well-highlighted by surgical, nutritional, and gastroenterological societies with the aim of reducing complications and enhancing recovery. Surgical procedures are frequently undertaken when other treatment options have been unsuccessful, and, thus, patients may have lost weight and/or required steroids, and are therefore at higher risk of post-operative complications. EEN is used extensively in the paediatric population to induce remission, but is not routinely used in the induction of remission of adult Crohn’s disease or in pre-operative optimisation. Large prospective studies regarding the role of pre-operative EEN are lacking. In this review, we evaluate the current literature on the use of EEN in pre-operative settings and its impact on patient outcomes.
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spelling pubmed-87092722021-12-25 Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease Shariff, Sharafaath Moran, Gordon Grimes, Caris Cooney, Rachel Margaret Nutrients Review Despite the increasing array of medications available for the treatment of Crohn’s disease and a focus on mucosal healing, approximately 35% of patients with Crohn’s disease undergo bowel surgery at some stage. The importance of nutritional optimisation before Crohn’s surgery is well-highlighted by surgical, nutritional, and gastroenterological societies with the aim of reducing complications and enhancing recovery. Surgical procedures are frequently undertaken when other treatment options have been unsuccessful, and, thus, patients may have lost weight and/or required steroids, and are therefore at higher risk of post-operative complications. EEN is used extensively in the paediatric population to induce remission, but is not routinely used in the induction of remission of adult Crohn’s disease or in pre-operative optimisation. Large prospective studies regarding the role of pre-operative EEN are lacking. In this review, we evaluate the current literature on the use of EEN in pre-operative settings and its impact on patient outcomes. MDPI 2021-12-08 /pmc/articles/PMC8709272/ /pubmed/34959941 http://dx.doi.org/10.3390/nu13124389 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Shariff, Sharafaath
Moran, Gordon
Grimes, Caris
Cooney, Rachel Margaret
Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease
title Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease
title_full Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease
title_fullStr Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease
title_full_unstemmed Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease
title_short Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease
title_sort current use of een in pre-operative optimisation in crohn’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709272/
https://www.ncbi.nlm.nih.gov/pubmed/34959941
http://dx.doi.org/10.3390/nu13124389
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