Cargando…
Drug Repurposing Using Modularity Clustering in Drug-Drug Similarity Networks Based on Drug–Gene Interactions
Drug repurposing is a valuable alternative to traditional drug design based on the assumption that medicines have multiple functions. Computer-based techniques use ever-growing drug databases to uncover new drug repurposing hints, which require further validation with in vitro and in vivo experiment...
Autores principales: | Groza, Vlad, Udrescu, Mihai, Bozdog, Alexandru, Udrescu, Lucreţia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709282/ https://www.ncbi.nlm.nih.gov/pubmed/34959398 http://dx.doi.org/10.3390/pharmaceutics13122117 |
Ejemplares similares
-
Clustering drug-drug interaction networks with energy model layouts: community analysis and drug repurposing
por: Udrescu, Lucreţia, et al.
Publicado: (2016) -
Uncovering New Drug Properties in Target-Based Drug–Drug Similarity Networks
por: Udrescu, Lucreţia, et al.
Publicado: (2020) -
The curse and blessing of abundance—the evolution of drug interaction databases and their impact on drug network analysis
por: Udrescu, Mihai, et al.
Publicado: (2023) -
Network science meets respiratory medicine for OSAS phenotyping and severity prediction
por: Mihaicuta, Stefan, et al.
Publicado: (2017) -
Gender Phenotyping of Patients with Obstructive Sleep Apnea Syndrome Using a Network Science Approach
por: Topîrceanu, Alexandru, et al.
Publicado: (2020)