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High-Phytate Diets Increase Amyloid β Deposition and Apoptotic Neuronal Cell Death in a Rat Model

Amyloid-β (Aβ) accumulation in the hippocampus is an essential event in the pathogenesis of Alzheimer’s disease. Insoluble Aβ is formed through the sequential proteolytic hydrolysis of the Aβ precursor protein, which is cleaved by proteolytic secretases. However, the pathophysiological mechanisms of...

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Detalles Bibliográficos
Autores principales:	Kim, Hyo-Jung, Jung, Yun-Shin, Jung, Yun-Jae, Kim, Ok-Hee, Oh, Byung-Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709321/ https://www.ncbi.nlm.nih.gov/pubmed/34959925 http://dx.doi.org/10.3390/nu13124370

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