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Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia

Pneumonia is one of the common complications of SARS-CoV-2 infection where most patients have moderate to severe symptoms that pose a higher risk for death. This study aims to evaluate the treatment outcome of COVID-19-associated Pneumonia among patients with/without comorbidity in a public hospital...

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Autores principales: Ramatillah, Diana Laila, Gan, Siew Hua, Sulaiman, Syed Azhar Syed, Puja, Dama, Abubakar, Usman, Jaber, Ammar Ali Saleh, Lukas, Stefanus, Jusnita, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709331/
https://www.ncbi.nlm.nih.gov/pubmed/34960157
http://dx.doi.org/10.3390/vaccines9121411
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author Ramatillah, Diana Laila
Gan, Siew Hua
Sulaiman, Syed Azhar Syed
Puja, Dama
Abubakar, Usman
Jaber, Ammar Ali Saleh
Lukas, Stefanus
Jusnita, Nina
author_facet Ramatillah, Diana Laila
Gan, Siew Hua
Sulaiman, Syed Azhar Syed
Puja, Dama
Abubakar, Usman
Jaber, Ammar Ali Saleh
Lukas, Stefanus
Jusnita, Nina
author_sort Ramatillah, Diana Laila
collection PubMed
description Pneumonia is one of the common complications of SARS-CoV-2 infection where most patients have moderate to severe symptoms that pose a higher risk for death. This study aims to evaluate the treatment outcome of COVID-19-associated Pneumonia among patients with/without comorbidity in a public hospital in Indonesia. This is a retrospective cohort study involving unvaccinated confirmed COVID-19 patients admitted to the hospital between March and December 2020. All confirmed COVID-19 patients with Pneumonia (n = 1522) treated at the hospital were included. The majority of patients (99%) had mild COVID-19 symptoms while the remaining had moderate symptoms. The median age was about 32 years old and the average treatment duration was 6.25 ± 1.83 days. Most patients (88.8%) received a combination of azithromycin and oseltamivir. There was a very significant relationship (p < 0.001) between comorbidities with treatment and duration of treatment of Pneumonia in COVID-19 patients. Although most patients had Pneumonia and comorbidities, they were successfully treated with azithromycin and oseltamivir combination following approximately five days of treatment.
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spelling pubmed-87093312021-12-25 Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia Ramatillah, Diana Laila Gan, Siew Hua Sulaiman, Syed Azhar Syed Puja, Dama Abubakar, Usman Jaber, Ammar Ali Saleh Lukas, Stefanus Jusnita, Nina Vaccines (Basel) Article Pneumonia is one of the common complications of SARS-CoV-2 infection where most patients have moderate to severe symptoms that pose a higher risk for death. This study aims to evaluate the treatment outcome of COVID-19-associated Pneumonia among patients with/without comorbidity in a public hospital in Indonesia. This is a retrospective cohort study involving unvaccinated confirmed COVID-19 patients admitted to the hospital between March and December 2020. All confirmed COVID-19 patients with Pneumonia (n = 1522) treated at the hospital were included. The majority of patients (99%) had mild COVID-19 symptoms while the remaining had moderate symptoms. The median age was about 32 years old and the average treatment duration was 6.25 ± 1.83 days. Most patients (88.8%) received a combination of azithromycin and oseltamivir. There was a very significant relationship (p < 0.001) between comorbidities with treatment and duration of treatment of Pneumonia in COVID-19 patients. Although most patients had Pneumonia and comorbidities, they were successfully treated with azithromycin and oseltamivir combination following approximately five days of treatment. MDPI 2021-11-30 /pmc/articles/PMC8709331/ /pubmed/34960157 http://dx.doi.org/10.3390/vaccines9121411 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ramatillah, Diana Laila
Gan, Siew Hua
Sulaiman, Syed Azhar Syed
Puja, Dama
Abubakar, Usman
Jaber, Ammar Ali Saleh
Lukas, Stefanus
Jusnita, Nina
Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
title Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
title_full Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
title_fullStr Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
title_full_unstemmed Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
title_short Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
title_sort evaluation of treatment outcome for pneumonia among pre-vaccinated covid-19 patients with/without comorbidity in a public hospital in bengkulu, indonesia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709331/
https://www.ncbi.nlm.nih.gov/pubmed/34960157
http://dx.doi.org/10.3390/vaccines9121411
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