Cargando…
Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
Pneumonia is one of the common complications of SARS-CoV-2 infection where most patients have moderate to severe symptoms that pose a higher risk for death. This study aims to evaluate the treatment outcome of COVID-19-associated Pneumonia among patients with/without comorbidity in a public hospital...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709331/ https://www.ncbi.nlm.nih.gov/pubmed/34960157 http://dx.doi.org/10.3390/vaccines9121411 |
_version_ | 1784622908746760192 |
---|---|
author | Ramatillah, Diana Laila Gan, Siew Hua Sulaiman, Syed Azhar Syed Puja, Dama Abubakar, Usman Jaber, Ammar Ali Saleh Lukas, Stefanus Jusnita, Nina |
author_facet | Ramatillah, Diana Laila Gan, Siew Hua Sulaiman, Syed Azhar Syed Puja, Dama Abubakar, Usman Jaber, Ammar Ali Saleh Lukas, Stefanus Jusnita, Nina |
author_sort | Ramatillah, Diana Laila |
collection | PubMed |
description | Pneumonia is one of the common complications of SARS-CoV-2 infection where most patients have moderate to severe symptoms that pose a higher risk for death. This study aims to evaluate the treatment outcome of COVID-19-associated Pneumonia among patients with/without comorbidity in a public hospital in Indonesia. This is a retrospective cohort study involving unvaccinated confirmed COVID-19 patients admitted to the hospital between March and December 2020. All confirmed COVID-19 patients with Pneumonia (n = 1522) treated at the hospital were included. The majority of patients (99%) had mild COVID-19 symptoms while the remaining had moderate symptoms. The median age was about 32 years old and the average treatment duration was 6.25 ± 1.83 days. Most patients (88.8%) received a combination of azithromycin and oseltamivir. There was a very significant relationship (p < 0.001) between comorbidities with treatment and duration of treatment of Pneumonia in COVID-19 patients. Although most patients had Pneumonia and comorbidities, they were successfully treated with azithromycin and oseltamivir combination following approximately five days of treatment. |
format | Online Article Text |
id | pubmed-8709331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87093312021-12-25 Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia Ramatillah, Diana Laila Gan, Siew Hua Sulaiman, Syed Azhar Syed Puja, Dama Abubakar, Usman Jaber, Ammar Ali Saleh Lukas, Stefanus Jusnita, Nina Vaccines (Basel) Article Pneumonia is one of the common complications of SARS-CoV-2 infection where most patients have moderate to severe symptoms that pose a higher risk for death. This study aims to evaluate the treatment outcome of COVID-19-associated Pneumonia among patients with/without comorbidity in a public hospital in Indonesia. This is a retrospective cohort study involving unvaccinated confirmed COVID-19 patients admitted to the hospital between March and December 2020. All confirmed COVID-19 patients with Pneumonia (n = 1522) treated at the hospital were included. The majority of patients (99%) had mild COVID-19 symptoms while the remaining had moderate symptoms. The median age was about 32 years old and the average treatment duration was 6.25 ± 1.83 days. Most patients (88.8%) received a combination of azithromycin and oseltamivir. There was a very significant relationship (p < 0.001) between comorbidities with treatment and duration of treatment of Pneumonia in COVID-19 patients. Although most patients had Pneumonia and comorbidities, they were successfully treated with azithromycin and oseltamivir combination following approximately five days of treatment. MDPI 2021-11-30 /pmc/articles/PMC8709331/ /pubmed/34960157 http://dx.doi.org/10.3390/vaccines9121411 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ramatillah, Diana Laila Gan, Siew Hua Sulaiman, Syed Azhar Syed Puja, Dama Abubakar, Usman Jaber, Ammar Ali Saleh Lukas, Stefanus Jusnita, Nina Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia |
title | Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia |
title_full | Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia |
title_fullStr | Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia |
title_full_unstemmed | Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia |
title_short | Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia |
title_sort | evaluation of treatment outcome for pneumonia among pre-vaccinated covid-19 patients with/without comorbidity in a public hospital in bengkulu, indonesia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709331/ https://www.ncbi.nlm.nih.gov/pubmed/34960157 http://dx.doi.org/10.3390/vaccines9121411 |
work_keys_str_mv | AT ramatillahdianalaila evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia AT gansiewhua evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia AT sulaimansyedazharsyed evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia AT pujadama evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia AT abubakarusman evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia AT jaberammaralisaleh evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia AT lukasstefanus evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia AT jusnitanina evaluationoftreatmentoutcomeforpneumoniaamongprevaccinatedcovid19patientswithwithoutcomorbidityinapublichospitalinbengkuluindonesia |