Probing Allosteric Hsp70 Inhibitors by Molecular Modelling Studies to Expedite the Development of Novel Combined F508del CFTR Modulators

Cystic fibrosis (CF) is caused by different mutations related to the cystic fibrosis transmembrane regulator protein (CFTR), with F508del being the most common. Pioneering the development of CFTR modulators, thanks to the development of effective correctors or potentiators, more recent studies deepl...

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Detalles Bibliográficos
Autores principales: Sabbadini, Roberto, Pesce, Emanuela, Parodi, Alice, Mustorgi, Eleonora, Bruzzone, Santina, Pedemonte, Nicoletta, Casale, Monica, Millo, Enrico, Cichero, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709398/
https://www.ncbi.nlm.nih.gov/pubmed/34959696
http://dx.doi.org/10.3390/ph14121296

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