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A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines

Aptamers constitute an answer for the growing need for targeted therapy development. One of the most well-known representatives of this group of compounds is thrombin binding aptamers (TBA) targeted towards thrombin. The TBA inhibitory activity is determined by its spatial arrangement, which consist...

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Detalles Bibliográficos
Autores principales: Kotkowiak, Weronika, Jahnz-Wechmann, Zofia, Pasternak, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709445/
https://www.ncbi.nlm.nih.gov/pubmed/34959726
http://dx.doi.org/10.3390/ph14121326