Cargando…

Enhanced Skin Delivery of Therapeutic Peptides Using Spicule-Based Topical Delivery Systems

This study reports two therapeutic peptides, insulin (INS, as a hydrophilic model peptide) and cyclosporine A (CysA, as a hydrophobic one), that can be administrated through a transdermal or dermal route by using spicule-based topical delivery systems in vitro and in vivo. We obtained a series of sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chi, Duan, Jiwen, Huang, Yongxiang, Chen, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709454/
https://www.ncbi.nlm.nih.gov/pubmed/34959402
http://dx.doi.org/10.3390/pharmaceutics13122119