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Enhanced Skin Delivery of Therapeutic Peptides Using Spicule-Based Topical Delivery Systems
This study reports two therapeutic peptides, insulin (INS, as a hydrophilic model peptide) and cyclosporine A (CysA, as a hydrophobic one), that can be administrated through a transdermal or dermal route by using spicule-based topical delivery systems in vitro and in vivo. We obtained a series of sp...
Autores principales: | Zhang, Chi, Duan, Jiwen, Huang, Yongxiang, Chen, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709454/ https://www.ncbi.nlm.nih.gov/pubmed/34959402 http://dx.doi.org/10.3390/pharmaceutics13122119 |
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