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The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog
Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by Achromobacter xylosoxidans, leading to an infectious endocarditis. Achromobacter xy...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709460/ https://www.ncbi.nlm.nih.gov/pubmed/34959535 http://dx.doi.org/10.3390/pathogens10121580 |
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author | Steiner, Verena Rosel, Adriana Cabal Ruppitsch, Werner Allerberger, Franz Carranza Valencia, Alejandra Markovic, Mato Luckschander-Zeller, Nicole Szostak, Michael P. Spergser, Joachim Loncaric, Igor Künzel, Frank |
author_facet | Steiner, Verena Rosel, Adriana Cabal Ruppitsch, Werner Allerberger, Franz Carranza Valencia, Alejandra Markovic, Mato Luckschander-Zeller, Nicole Szostak, Michael P. Spergser, Joachim Loncaric, Igor Künzel, Frank |
author_sort | Steiner, Verena |
collection | PubMed |
description | Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by Achromobacter xylosoxidans, leading to an infectious endocarditis. Achromobacter xylosoxidans (A. xylosoxidans) is an aerobic Gram-negative rod-shaped bacterium, which has been associated with multiple nosocomial opportunistic diseases in human medicine. One such manifestation of A. xylosoxidans infection is endocarditis. A. xylosoxidans infections are challenging to treat due to the reduced effectiveness of a wide range of antimicrobial agents. To date, only a few case reports of infections with A. xylosoxidans in animals have been described. This is the first case report of A. xylosoxidans endocarditis in a dog. Whole-genome sequencing was performed to determine the sequencing type and to gain more information about this bacterium regarding its intrinsic resistance genes. With this case report, we seek to increase awareness of A. xylosoxidans as an opportunistic nosocomial pathogen in dogs and to provide a short summary regarding the current state of general knowledge and known resistance patterns. |
format | Online Article Text |
id | pubmed-8709460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87094602021-12-25 The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog Steiner, Verena Rosel, Adriana Cabal Ruppitsch, Werner Allerberger, Franz Carranza Valencia, Alejandra Markovic, Mato Luckschander-Zeller, Nicole Szostak, Michael P. Spergser, Joachim Loncaric, Igor Künzel, Frank Pathogens Case Report Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by Achromobacter xylosoxidans, leading to an infectious endocarditis. Achromobacter xylosoxidans (A. xylosoxidans) is an aerobic Gram-negative rod-shaped bacterium, which has been associated with multiple nosocomial opportunistic diseases in human medicine. One such manifestation of A. xylosoxidans infection is endocarditis. A. xylosoxidans infections are challenging to treat due to the reduced effectiveness of a wide range of antimicrobial agents. To date, only a few case reports of infections with A. xylosoxidans in animals have been described. This is the first case report of A. xylosoxidans endocarditis in a dog. Whole-genome sequencing was performed to determine the sequencing type and to gain more information about this bacterium regarding its intrinsic resistance genes. With this case report, we seek to increase awareness of A. xylosoxidans as an opportunistic nosocomial pathogen in dogs and to provide a short summary regarding the current state of general knowledge and known resistance patterns. MDPI 2021-12-03 /pmc/articles/PMC8709460/ /pubmed/34959535 http://dx.doi.org/10.3390/pathogens10121580 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Steiner, Verena Rosel, Adriana Cabal Ruppitsch, Werner Allerberger, Franz Carranza Valencia, Alejandra Markovic, Mato Luckschander-Zeller, Nicole Szostak, Michael P. Spergser, Joachim Loncaric, Igor Künzel, Frank The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog |
title | The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog |
title_full | The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog |
title_fullStr | The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog |
title_full_unstemmed | The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog |
title_short | The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog |
title_sort | first bacterial endocarditis due to achromobacter xylosoxidans in a dog |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709460/ https://www.ncbi.nlm.nih.gov/pubmed/34959535 http://dx.doi.org/10.3390/pathogens10121580 |
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