Cargando…

The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog

Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by Achromobacter xylosoxidans, leading to an infectious endocarditis. Achromobacter xy...

Descripción completa

Detalles Bibliográficos
Autores principales: Steiner, Verena, Rosel, Adriana Cabal, Ruppitsch, Werner, Allerberger, Franz, Carranza Valencia, Alejandra, Markovic, Mato, Luckschander-Zeller, Nicole, Szostak, Michael P., Spergser, Joachim, Loncaric, Igor, Künzel, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709460/
https://www.ncbi.nlm.nih.gov/pubmed/34959535
http://dx.doi.org/10.3390/pathogens10121580
_version_ 1784622940723085312
author Steiner, Verena
Rosel, Adriana Cabal
Ruppitsch, Werner
Allerberger, Franz
Carranza Valencia, Alejandra
Markovic, Mato
Luckschander-Zeller, Nicole
Szostak, Michael P.
Spergser, Joachim
Loncaric, Igor
Künzel, Frank
author_facet Steiner, Verena
Rosel, Adriana Cabal
Ruppitsch, Werner
Allerberger, Franz
Carranza Valencia, Alejandra
Markovic, Mato
Luckschander-Zeller, Nicole
Szostak, Michael P.
Spergser, Joachim
Loncaric, Igor
Künzel, Frank
author_sort Steiner, Verena
collection PubMed
description Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by Achromobacter xylosoxidans, leading to an infectious endocarditis. Achromobacter xylosoxidans (A. xylosoxidans) is an aerobic Gram-negative rod-shaped bacterium, which has been associated with multiple nosocomial opportunistic diseases in human medicine. One such manifestation of A. xylosoxidans infection is endocarditis. A. xylosoxidans infections are challenging to treat due to the reduced effectiveness of a wide range of antimicrobial agents. To date, only a few case reports of infections with A. xylosoxidans in animals have been described. This is the first case report of A. xylosoxidans endocarditis in a dog. Whole-genome sequencing was performed to determine the sequencing type and to gain more information about this bacterium regarding its intrinsic resistance genes. With this case report, we seek to increase awareness of A. xylosoxidans as an opportunistic nosocomial pathogen in dogs and to provide a short summary regarding the current state of general knowledge and known resistance patterns.
format Online
Article
Text
id pubmed-8709460
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-87094602021-12-25 The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog Steiner, Verena Rosel, Adriana Cabal Ruppitsch, Werner Allerberger, Franz Carranza Valencia, Alejandra Markovic, Mato Luckschander-Zeller, Nicole Szostak, Michael P. Spergser, Joachim Loncaric, Igor Künzel, Frank Pathogens Case Report Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by Achromobacter xylosoxidans, leading to an infectious endocarditis. Achromobacter xylosoxidans (A. xylosoxidans) is an aerobic Gram-negative rod-shaped bacterium, which has been associated with multiple nosocomial opportunistic diseases in human medicine. One such manifestation of A. xylosoxidans infection is endocarditis. A. xylosoxidans infections are challenging to treat due to the reduced effectiveness of a wide range of antimicrobial agents. To date, only a few case reports of infections with A. xylosoxidans in animals have been described. This is the first case report of A. xylosoxidans endocarditis in a dog. Whole-genome sequencing was performed to determine the sequencing type and to gain more information about this bacterium regarding its intrinsic resistance genes. With this case report, we seek to increase awareness of A. xylosoxidans as an opportunistic nosocomial pathogen in dogs and to provide a short summary regarding the current state of general knowledge and known resistance patterns. MDPI 2021-12-03 /pmc/articles/PMC8709460/ /pubmed/34959535 http://dx.doi.org/10.3390/pathogens10121580 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Steiner, Verena
Rosel, Adriana Cabal
Ruppitsch, Werner
Allerberger, Franz
Carranza Valencia, Alejandra
Markovic, Mato
Luckschander-Zeller, Nicole
Szostak, Michael P.
Spergser, Joachim
Loncaric, Igor
Künzel, Frank
The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog
title The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog
title_full The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog
title_fullStr The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog
title_full_unstemmed The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog
title_short The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog
title_sort first bacterial endocarditis due to achromobacter xylosoxidans in a dog
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709460/
https://www.ncbi.nlm.nih.gov/pubmed/34959535
http://dx.doi.org/10.3390/pathogens10121580
work_keys_str_mv AT steinerverena thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT roseladrianacabal thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT ruppitschwerner thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT allerbergerfranz thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT carranzavalenciaalejandra thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT markovicmato thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT luckschanderzellernicole thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT szostakmichaelp thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT spergserjoachim thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT loncaricigor thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT kunzelfrank thefirstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT steinerverena firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT roseladrianacabal firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT ruppitschwerner firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT allerbergerfranz firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT carranzavalenciaalejandra firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT markovicmato firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT luckschanderzellernicole firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT szostakmichaelp firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT spergserjoachim firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT loncaricigor firstbacterialendocarditisduetoachromobacterxylosoxidansinadog
AT kunzelfrank firstbacterialendocarditisduetoachromobacterxylosoxidansinadog