Cargando…

Akt Signaling Pathway Is Activated in the Minor Salivary Glands of Patients with Primary Sjögren’s Syndrome

Primary Sjögren’s syndrome (pSS) is an autoimmune exocrinopathy of mainly the salivary and lacrimal glands associated with high prevalence of lymphoma. Akt is a phosphoinositide-dependent serine/threonine kinase, controlling numerous pathological processes, including oncogenesis and autoimmunity. He...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stergiou, Ioanna E., Chatzis, Loukas, Papanikolaou, Asimina, Giannouli, Stavroula, Tzioufas, Athanasios G., Voulgarelis, Michael, Kapsogeorgou, Efstathia K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709495/ https://www.ncbi.nlm.nih.gov/pubmed/34948236 http://dx.doi.org/10.3390/ijms222413441

Ejemplares similares

Serum, but Not Saliva, CXCL13 Levels Associate With Infiltrating CXCL13+ Cells in the Minor Salivary Gland Lesions and Other Histologic Parameters in Patients With Sjögren’s Syndrome
por: Chatzis, Loukas, et al.
Publicado: (2021)

The Role of the Akt Signaling Pathway in Sjögren’s Syndrome
por: Kapsogeorgou, Efstathia K., et al.
Publicado: (2023)

Clinical Phenotype and Mechanisms of Leukopenia/Neutropenia in Patients with Primary Sjögren’s Syndrome
por: Stergiou, Ioanna E., et al.
Publicado: (2022)

Interaction of Human Salivary Gland Epithelial Cells with B Lymphocytes: Implications in the Pathogenesis of Sjögren’s Syndrome
por: Kapsogeorgou, Efstathia K., et al.
Publicado: (2020)

Role of miR200b-5p miRNA in lymphomagenesis associated with Sjögren’s syndrome (SS)
por: Kapsogeorgou, Efstathia K., et al.
Publicado: (2018)

DNA Methylation Studies in Saliva of Patients with Sjögren’s Syndrome
por: Karagianni, Panagiota, et al.
Publicado: (2021)

Perturbation of transcriptome in non-neoplastic salivary gland epithelial cell lines derived from patients with primary Sjögren's syndrome
por: Vakrakou, Aigli G., et al.
Publicado: (2017)

Minor Salivary Gland Biopsy in Diagnosis of Sjögren’s Syndrome
por: Gordon, Alex J., et al.
Publicado: (2022)

Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren’s Syndrome
por: Oyelakin, Akinsola, et al.
Publicado: (2021)

Autophagy and Metabolism in Normal and Malignant Hematopoiesis
por: Stergiou, Ioanna E., et al.
Publicado: (2021)

Pathogenetic Mechanisms Implicated in Sjögren’s Syndrome Lymphomagenesis: A Review of the Literature
por: Stergiou, Ioanna E., et al.
Publicado: (2020)

Liver Fibrosis in Primary Sjögren’s Syndrome
por: Androutsakos, Theodoros, et al.
Publicado: (2022)

Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome
por: Fisher, Benjamin A, et al.
Publicado: (2017)

The Transcriptome of Paired Major and Minor Salivary Gland Tissue in Patients With Primary Sjögren’s Syndrome
por: Verstappen, Gwenny M., et al.
Publicado: (2021)

TNFAIP3 F127C Coding Variation in Greek Primary Sjogren's Syndrome Patients
por: Nezos, Adrianos, et al.
Publicado: (2018)

Lipoprotein-Associated Phospholipase A2: A Novel Contributor in Sjögren’s Syndrome-Related Lymphoma?
por: Nezos, Adrianos, et al.
Publicado: (2021)

Deregulation of the Kallikrein Protease Family in the Salivary Glands of the Sjögren’s Syndrome ERdj5 Knockout Mouse Model
por: Moustardas, Petros, et al.
Publicado: (2021)

Long non-coding RNA expression profile in minor salivary gland of primary Sjögren’s syndrome
por: Shi, Huan, et al.
Publicado: (2016)

Expression of innate immune receptors in the immunopathologic lesion of primary Sjogren's syndrome: preliminary results
por: Bourazopoulou, E, et al.
Publicado: (2005)

Bioenergetic Profiling of the Differentiating Human MDS Myeloid Lineage with Low and High Bone Marrow Blast Counts
por: Poulaki, Aikaterini, et al.
Publicado: (2020)

Autophagy occurs in lymphocytes infiltrating Sjögren’s syndrome minor salivary glands and correlates with histological severity of salivary gland lesions
por: Colafrancesco, Serena, et al.
Publicado: (2020)

The Significance of Ectopic Germinal Centers in the Minor Salivary Gland of Patients with Sjögren’s Syndrome
por: Lee, Kyung-Eun, et al.
Publicado: (2016)

Evaluation of sialometry and minor salivary gland biopsy in classification of Sjögren's Syndrome patients
por: Liquidato, Bianca Maria, et al.
Publicado: (2015)

Expression of IL-17, IL-23 and Their Receptors in Minor Salivary Glands of Patients with Primary Sjögren's Syndrome
por: Mieliauskaite, Diana, et al.
Publicado: (2012)

Telocytes in minor salivary glands of primary Sjögren’s syndrome: association with the extent of inflammation and ectopic lymphoid neogenesis
por: Alunno, Alessia, et al.
Publicado: (2015)

Evaluation of histopathological results of minor salivary gland biopsies in patients with the diagnosis of Sjögren’s syndrome
por: Erkılınç, Gamze, et al.
Publicado: (2021)

Correlations between the histopathological alterations in minor salivary glands and the clinically suspected Sjögren’s syndrome
por: Janka, Mária, et al.
Publicado: (2023)

Inflammatory Stratification in Primary Sjögren’s Syndrome Reveals Novel Immune Cell Alterations in Patients’ Minor Salivary Glands
por: Bharaj, Tamandeep K., et al.
Publicado: (2021)

Diagnostic Utility of Minor Salivary Gland Biopsy for Primary Sjögren Syndrome in Patients With Negative Anti-SSA Antibodies
por: Goel, Rohit R, et al.
Publicado: (2023)

Cultured salivary gland epithelial cells release exosomes that contain the Sjögren's-syndrome-associated autoantigenic ribonucleoproteins Ro/SSA and La/SSB
por: Kapsogeorgou, EK, et al.
Publicado: (2003)

Ultrasonographic Changes of Major Salivary Glands in Primary Sjögren’s Syndrome
por: Lee, Kyung-Ann, et al.
Publicado: (2020)

High spontaneous CD40 expression by salivary gland epithelial cells in Sjogren's syndrome: possible evidence for intrinsic activation of epithelial cells
por: Dimitriou, ID, et al.
Publicado: (2001)

Predicting the Outcome of Sjogren’s Syndrome-Associated Non-Hodgkin’s Lymphoma Patients
por: Papageorgiou, Aristea, et al.
Publicado: (2015)

Different operators and histologic techniques in the assessment of germinal center-like structures in primary Sjögren’s syndrome minor salivary glands
por: Carubbi, Francesco, et al.
Publicado: (2019)

Neurologic involvement in seronegative primary Sjögren’s syndrome with positive minor salivary gland biopsy: a single-center experience
por: Hoshina, Yoji, et al.
Publicado: (2023)

Role of the mTOR pathway in minor salivary gland changes in Sjogren’s syndrome and systemic sclerosis
por: Soypaçacı, Zeki, et al.
Publicado: (2018)

Exploiting the Role of Hypoxia-Inducible Factor 1 and Pseudohypoxia in the Myelodysplastic Syndrome Pathophysiology
por: Stergiou, Ioanna E., et al.
Publicado: (2021)

Cultured salivary gland epithelial cells from patients with primary Sjögren's syndrome and disease controls are sensitive to signaling via Toll-like receptors 2 and 3: upregulation of intercellular adhesion molecule-1 expression
por: Spachidou, MP, et al.
Publicado: (2005)

From the (Epi)Genome to Metabolism and Vice Versa; Examples from Hematologic Malignancy
por: Karagianni, Panagiota, et al.
Publicado: (2021)

Salivary Gland Stem Cells Age Prematurely in Primary Sjögren's Syndrome
por: Pringle, Sarah, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ev8bticgkdm1lrgkukja4qm15p