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Compartmentalized Polymeric Nanoparticles Deliver Vancomycin in a pH-Responsive Manner
Vancomycin (VCM) is a last resort antibiotic in the treatment of severe Gram-positive infections. However, its administration is limited by several drawbacks such as: strong pH-dependent charge, tendency to aggregate, low bioavailability, and poor cellular uptake. These drawbacks were circumvented b...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709497/ https://www.ncbi.nlm.nih.gov/pubmed/34959274 http://dx.doi.org/10.3390/pharmaceutics13121992 |