A cell-type-specific atlas of the inner ear transcriptional response to acoustic trauma

Noise-induced hearing loss (NIHL) results from a complex interplay of damage to the sensory cells of the inner ear, dysfunction of its lateral wall, axonal retraction of type 1C spiral ganglion neurons, and activation of the immune response. We use RiboTag and single-cell RNA sequencing to survey th...

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Detalles Bibliográficos
Autores principales: Milon, Beatrice, Shulman, Eldad D., So, Kathy S., Cederroth, Christopher R., Lipford, Erika L., Sperber, Michal, Sellon, Jonathan B., Sarlus, Heela, Pregernig, Gabriela, Shuster, Benjamin, Song, Yang, Mitra, Sunayana, Orvis, Joshua, Margulies, Zachary, Ogawa, Yoko, Shults, Christopher, Depireux, Didier A., Palermo, Adam T., Canlon, Barbara, Burns, Joe, Elkon, Ran, Hertzano, Ronna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709734/
https://www.ncbi.nlm.nih.gov/pubmed/34592158
http://dx.doi.org/10.1016/j.celrep.2021.109758

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