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Future implications of COVID-19 through Mathematical modeling

COVID-19 is a pandemic respiratory illness. The disease spreads from human to human and is caused by a novel coronavirus SARS-CoV-2. In this study, we formulate a mathematical model of COVID-19 and discuss the disease free state and endemic equilibrium of the model. Based on the sensitivity indexes...

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Autores principales: Zamir, Muhammad, Nadeem, Fawad, Alqudah, Manar A., Abdeljawad, Thabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709924/
https://www.ncbi.nlm.nih.gov/pubmed/34976710
http://dx.doi.org/10.1016/j.rinp.2021.105097
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author Zamir, Muhammad
Nadeem, Fawad
Alqudah, Manar A.
Abdeljawad, Thabet
author_facet Zamir, Muhammad
Nadeem, Fawad
Alqudah, Manar A.
Abdeljawad, Thabet
author_sort Zamir, Muhammad
collection PubMed
description COVID-19 is a pandemic respiratory illness. The disease spreads from human to human and is caused by a novel coronavirus SARS-CoV-2. In this study, we formulate a mathematical model of COVID-19 and discuss the disease free state and endemic equilibrium of the model. Based on the sensitivity indexes of the parameters, control strategies are designed. The strategies reduce the densities of the infected classes but do not satisfy the criteria/threshold condition of the global stability of disease free equilibrium. On the other hand, the endemic equilibrium of the disease is globally asymptotically stable. Therefore it is concluded that the disease cannot be eradicated with present resources and the human population needs to learn how to live with corona. For validation of the results, numerical simulations are obtained using fourth order Runge–Kutta method.
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spelling pubmed-87099242021-12-28 Future implications of COVID-19 through Mathematical modeling Zamir, Muhammad Nadeem, Fawad Alqudah, Manar A. Abdeljawad, Thabet Results Phys Article COVID-19 is a pandemic respiratory illness. The disease spreads from human to human and is caused by a novel coronavirus SARS-CoV-2. In this study, we formulate a mathematical model of COVID-19 and discuss the disease free state and endemic equilibrium of the model. Based on the sensitivity indexes of the parameters, control strategies are designed. The strategies reduce the densities of the infected classes but do not satisfy the criteria/threshold condition of the global stability of disease free equilibrium. On the other hand, the endemic equilibrium of the disease is globally asymptotically stable. Therefore it is concluded that the disease cannot be eradicated with present resources and the human population needs to learn how to live with corona. For validation of the results, numerical simulations are obtained using fourth order Runge–Kutta method. The Authors. Published by Elsevier B.V. 2022-02 2021-12-25 /pmc/articles/PMC8709924/ /pubmed/34976710 http://dx.doi.org/10.1016/j.rinp.2021.105097 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Zamir, Muhammad
Nadeem, Fawad
Alqudah, Manar A.
Abdeljawad, Thabet
Future implications of COVID-19 through Mathematical modeling
title Future implications of COVID-19 through Mathematical modeling
title_full Future implications of COVID-19 through Mathematical modeling
title_fullStr Future implications of COVID-19 through Mathematical modeling
title_full_unstemmed Future implications of COVID-19 through Mathematical modeling
title_short Future implications of COVID-19 through Mathematical modeling
title_sort future implications of covid-19 through mathematical modeling
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709924/
https://www.ncbi.nlm.nih.gov/pubmed/34976710
http://dx.doi.org/10.1016/j.rinp.2021.105097
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