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Cordycepin augments the chemosensitivity of osteosarcoma to cisplatin by activating AMPK and suppressing the AKT signaling pathway

BACKGROUND: Osteosarcoma is the most common primary bone tumor in children and adolescents. However, some patients with osteosarcoma develop resistance to chemotherapy, leading to a poor clinical prognosis. Hence, effective therapeutic agents that can improve the response to chemotherapy drugs to im...

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Detalles Bibliográficos
Autores principales: Li, Hong-Bo, Chen, Jun-Kai, Su, Ze-Xin, Jin, Qing-Lin, Deng, Li-Wen, Huang, Gang, Shen, Jing-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709946/
https://www.ncbi.nlm.nih.gov/pubmed/34953496
http://dx.doi.org/10.1186/s12935-021-02411-y