Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism

Traditional Chinese medicines are an important class of natural products mainly derives from animals, plants and minerals, most of which need to be improved and processed before clinical use due to their own hard texture, impurities or toxicity. As an important part of solid excipients, mineral exci...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Li, Xiaojie, Chen, Cai, Leng, Aijing, Qu, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709976/
https://www.ncbi.nlm.nih.gov/pubmed/34952619
http://dx.doi.org/10.1186/s13020-021-00554-8
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author Liu, Yan
Li, Xiaojie
Chen, Cai
Leng, Aijing
Qu, Jialin
author_facet Liu, Yan
Li, Xiaojie
Chen, Cai
Leng, Aijing
Qu, Jialin
author_sort Liu, Yan
collection PubMed
description Traditional Chinese medicines are an important class of natural products mainly derives from animals, plants and minerals, most of which need to be improved and processed before clinical use due to their own hard texture, impurities or toxicity. As an important part of solid excipients, mineral excipients that contain some metal elements play indispensable and unique roles in the pretreatment process of traditional Chinese medicine. However, deficiency of holistic understanding of the effect of mineral excipients hinders their application and development. This article reviews several mineral excipients including alumen, talci pulvis, soil, soda lime, halloysitum rubrum and cinnabaris systemically. Their processing significance on traditional Chinese medicines were revealed from components, pharmacodynamics and mechanism aspects. Furthermore, prospect and problems including processing technologies, quality standards of mineral excipients and processing mechanism were put forward. This review supply comprehensive information for better and scientific usage of mineral excipients in processing traditional Chinese medicines.
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spelling pubmed-87099762022-01-05 Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism Liu, Yan Li, Xiaojie Chen, Cai Leng, Aijing Qu, Jialin Chin Med Review Traditional Chinese medicines are an important class of natural products mainly derives from animals, plants and minerals, most of which need to be improved and processed before clinical use due to their own hard texture, impurities or toxicity. As an important part of solid excipients, mineral excipients that contain some metal elements play indispensable and unique roles in the pretreatment process of traditional Chinese medicine. However, deficiency of holistic understanding of the effect of mineral excipients hinders their application and development. This article reviews several mineral excipients including alumen, talci pulvis, soil, soda lime, halloysitum rubrum and cinnabaris systemically. Their processing significance on traditional Chinese medicines were revealed from components, pharmacodynamics and mechanism aspects. Furthermore, prospect and problems including processing technologies, quality standards of mineral excipients and processing mechanism were put forward. This review supply comprehensive information for better and scientific usage of mineral excipients in processing traditional Chinese medicines. BioMed Central 2021-12-24 /pmc/articles/PMC8709976/ /pubmed/34952619 http://dx.doi.org/10.1186/s13020-021-00554-8 Text en © The Author(s) 2021, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Liu, Yan
Li, Xiaojie
Chen, Cai
Leng, Aijing
Qu, Jialin
Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism
title Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism
title_full Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism
title_fullStr Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism
title_full_unstemmed Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism
title_short Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism
title_sort effect of mineral excipients on processing traditional chinese medicines: an insight into the components, pharmacodynamics and mechanism
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709976/
https://www.ncbi.nlm.nih.gov/pubmed/34952619
http://dx.doi.org/10.1186/s13020-021-00554-8
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