Biomimetic nanoparticles blocking autophagy for enhanced chemotherapy and metastasis inhibition via reversing focal adhesion disassembly

BACKGROUND: Autophagy is a conserved catabolic process, which plays an important role in regulating tumor cell motility and degrading protein aggregates. Chemotherapy-induced autophagy may lead to tumor distant metastasis and even chemo-insensitivity in the therapy of hepatocellular carcinoma (HCC)....

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Detalles Bibliográficos
Autores principales: Shi, Yesi, Lin, Gan, Zheng, Huili, Mu, Dan, Chen, Hu, Lu, Zhixiang, He, Pan, Zhang, Yang, Liu, Chao, Lin, Zhongning, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710033/
https://www.ncbi.nlm.nih.gov/pubmed/34952594
http://dx.doi.org/10.1186/s12951-021-01189-5

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