Cargando…

Transcriptomic identification of HBx-associated hub genes in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignancies around the world. Among the risk factors involved in liver carcinogenesis, hepatitis B virus (HBV) X protein (HBx) is considered to be a key regulator in hepatocarcinogenesis. Whether HBx promotes or protects against H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ni, Zhengzhong, Lu, Jun, Huang, Weiyi, Khan, Hanif, Wu, Xuejun, Huang, Danmei, Shi, Ganggang, Niu, Yongdong, Huang, Haihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710059/ https://www.ncbi.nlm.nih.gov/pubmed/35036167 http://dx.doi.org/10.7717/peerj.12697

Ejemplares similares

C-Terminal Truncated HBx Facilitates Oncogenesis by Modulating Cell Cycle and Glucose Metabolism in FXR-Deficient Hepatocellular Carcinoma
por: Wu, Xuejun, et al.
Publicado: (2023)

Mechanism of HBx carcinogenesis interaction with non-coding RNA in hepatocellular carcinoma
por: Wang, Zhuoran, et al.
Publicado: (2023)

Autophagic Degradation of Misfolded Nuclear Receptor Co-repressor (NCoR) Is Linked to the Growth of Tumor Cells in HBX Positive Hepatocellular Carcinoma (HCC)
por: Tan, Su Yin, et al.
Publicado: (2019)

Identification and Validation of Hub Genes Associated With Hepatocellular Carcinoma Via Integrated Bioinformatics Analysis
por: Wang, Sumei, et al.
Publicado: (2021)

Identification of the hub genes associated with prostate cancer tumorigenesis
por: Zhu, Honghui, et al.
Publicado: (2023)

Identification of Hub Genes Associated With Clear Cell Renal Cell Carcinoma by Integrated Bioinformatics Analysis
por: Huang, Hao, et al.
Publicado: (2021)

Interaction of Hepatitis B Virus X Protein with the Pregnane X Receptor Enhances the Synergistic Effects of Aflatoxin B1 and Hepatitis B Virus on Promoting Hepatocarcinogenesis
por: Niu, Yongdong, et al.
Publicado: (2021)

Identification of hub genes involved in the development of hepatocellular carcinoma by transcriptome sequencing
por: Zheng, Yongchang, et al.
Publicado: (2017)

Integrated Transcriptomic Analysis Revealed Hub Genes and Pathways Involved in Sorafenib Resistance in Hepatocellular Carcinoma
por: Jiang, Xili, et al.
Publicado: (2021)

HBx‐mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis
por: Chen, Shi‐Lu, et al.
Publicado: (2017)

HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3
por: Chen, Jhen-Yu, et al.
Publicado: (2015)

HBx Gene Mutations in Hepatitis B Virus and Hepatocellular Carcinoma
por: Mathew M, Anumol, et al.
Publicado: (2014)

Identification of a 12-Gene Signature and Hub Genes Involved in Kidney Wilms Tumor via Integrated Bioinformatics Analysis
por: Huang, Guoping, et al.
Publicado: (2022)

Identification and Validation of a Prognostic lncRNA Signature for Hepatocellular Carcinoma
por: Li, Wang, et al.
Publicado: (2020)

Identification of hub genes and candidate drugs in hepatocellular carcinoma by integrated bioinformatics analysis
por: Chen, Xiaolong, et al.
Publicado: (2021)

A positive-feedback loop between HBx and ALKBH5 promotes hepatocellular carcinogenesis
por: Qu, Siming, et al.
Publicado: (2021)

Identification and Validation of Novel Biomarkers for Diagnosis and Prognosis of Hepatocellular Carcinoma
por: Hu, Xiaoyi, et al.
Publicado: (2020)

Identification of Hub Genes Associated With the Development of Stomach Adenocarcinoma by Integrated Bioinformatics Analysis
por: Zhang, Kehui, et al.
Publicado: (2022)

Verapamil Alleviates Myocardial Ischemia/Reperfusion Injury by Attenuating Oxidative Stress via Activation of SIRT1
por: Bao, Mi, et al.
Publicado: (2022)

Corrigendum: Identification and Validation of Novel Biomarkers for Diagnosis and Prognosis of Hepatocellular Carcinoma
por: Hu, Xiaoyi, et al.
Publicado: (2020)

Identification of Multiple Hub Genes and Pathways in Hepatocellular Carcinoma: A Bioinformatics Analysis
por: Liu, Junwei, et al.
Publicado: (2021)

HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress
por: Wang, Ming-Da, et al.
Publicado: (2016)

HBx protein‐mediated ATOH1 downregulation suppresses ARID2 expression and promotes hepatocellular carcinoma
por: Gao, Qingzhu, et al.
Publicado: (2017)

Integrative Analysis of Epigenome and Transcriptome Data Reveals Aberrantly Methylated Promoters and Enhancers in Hepatocellular Carcinoma
por: Huang, Peng, et al.
Publicado: (2021)

Identification of Hub Genes Associated With Melanoma Development by Comprehensive Bioinformatics Analysis
por: Jiang, Jie, et al.
Publicado: (2021)

Identification of hub genes and construction of prognostic nomogram for patients with Wilms tumors
por: Lou, Lei, et al.
Publicado: (2022)

HBX-induced miR-5188 impairs FOXO1 to stimulate β-catenin nuclear translocation and promotes tumor stemness in hepatocellular carcinoma
por: Lin, Xian, et al.
Publicado: (2019)

Identification and validation of immune-related hub genes based on machine learning in prostate cancer and AOX1 is an oxidative stress-related biomarker
por: Mo, Xiaocong, et al.
Publicado: (2023)

Farnesoid X receptor functions in cervical cancer via the p14(ARF)-mouse double minute 2-p53 pathway
por: Huang, Xiaohua, et al.
Publicado: (2022)

Identification of Hub Genes Associated With Development of Head and Neck Squamous Cell Carcinoma by Integrated Bioinformatics Analysis
por: Li, Chia Ying, et al.
Publicado: (2020)

Genome-wide identification of direct HBx genomic targets
por: Guerrieri, Francesca, et al.
Publicado: (2017)

Identification of Differentially Expressed Hub Genes Associated With Immune Cell Recruitment in Claudin-Low Breast Cancer
por: Wang, Yange, et al.
Publicado: (2022)

Identification of Ten Core Hub Genes as Potential Biomarkers and Treatment Target for Hepatoblastoma
por: Sun, Rui, et al.
Publicado: (2021)

Identification of Hub Genes Related to Liver Metastasis of Colorectal Cancer by Integrative Analysis
por: Liu, Sicheng, et al.
Publicado: (2021)

Erratum: Identification of hub genes and construction of prognostic nomogram for patients with Wilms tumors
Publicado: (2023)

Retraction: Identification of hub genes and construction of prognostic nomogram for patients with Wilms tumors
Publicado: (2023)

Identification of PAFAH1B3 as Candidate Prognosis Marker and Potential Therapeutic Target for Hepatocellular Carcinoma
por: Xu, Weikang, et al.
Publicado: (2021)

HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis
por: Wang, Qing, et al.
Publicado: (2020)

Utilizing Experimental Mouse Model to Identify Effectors of Hepatocellular Carcinoma Induced by HBx Antigen
por: Yang, Ming-Hui, et al.
Publicado: (2020)

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma
por: Medhat, Arvin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_q0jhljcgjtkrofsqbljn395oh7