Cargando…
Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles
The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field‐consensus rigour initiative of the International Society for Extracellular Vesicles (ISEV). The last update to MISEV, MISEV2018, was informed by input from more than 400 scientists and made recommendations in the s...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710080/ https://www.ncbi.nlm.nih.gov/pubmed/34953156 http://dx.doi.org/10.1002/jev2.12182 |
_version_ | 1784623083774017536 |
---|---|
author | Witwer, Kenneth W Goberdhan, Deborah CI O'Driscoll, Lorraine Théry, Clotilde Welsh, Joshua A Blenkiron, Cherie Buzás, Edit I Di Vizio, Dolores Erdbrügger, Uta Falcón‐Pérez, Juan M Fu, Qing‐Ling Hill, Andrew F Lenassi, Metka Lötvall, Jan Nieuwland, Rienk Ochiya, Takahiro Rome, Sophie Sahoo, Susmita Zheng, Lei |
author_facet | Witwer, Kenneth W Goberdhan, Deborah CI O'Driscoll, Lorraine Théry, Clotilde Welsh, Joshua A Blenkiron, Cherie Buzás, Edit I Di Vizio, Dolores Erdbrügger, Uta Falcón‐Pérez, Juan M Fu, Qing‐Ling Hill, Andrew F Lenassi, Metka Lötvall, Jan Nieuwland, Rienk Ochiya, Takahiro Rome, Sophie Sahoo, Susmita Zheng, Lei |
author_sort | Witwer, Kenneth W |
collection | PubMed |
description | The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field‐consensus rigour initiative of the International Society for Extracellular Vesicles (ISEV). The last update to MISEV, MISEV2018, was informed by input from more than 400 scientists and made recommendations in the six broad topics of EV nomenclature, sample collection and pre‐processing, EV separation and concentration, characterization, functional studies, and reporting requirements/exceptions. To gather opinions on MISEV and ideas for new updates, the ISEV Board of Directors canvassed previous MISEV authors and society members. Here, we share conclusions that are relevant to the ongoing evolution of the MISEV initiative and other ISEV rigour and standardization efforts. |
format | Online Article Text |
id | pubmed-8710080 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87100802022-01-04 Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles Witwer, Kenneth W Goberdhan, Deborah CI O'Driscoll, Lorraine Théry, Clotilde Welsh, Joshua A Blenkiron, Cherie Buzás, Edit I Di Vizio, Dolores Erdbrügger, Uta Falcón‐Pérez, Juan M Fu, Qing‐Ling Hill, Andrew F Lenassi, Metka Lötvall, Jan Nieuwland, Rienk Ochiya, Takahiro Rome, Sophie Sahoo, Susmita Zheng, Lei J Extracell Vesicles Editorial The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field‐consensus rigour initiative of the International Society for Extracellular Vesicles (ISEV). The last update to MISEV, MISEV2018, was informed by input from more than 400 scientists and made recommendations in the six broad topics of EV nomenclature, sample collection and pre‐processing, EV separation and concentration, characterization, functional studies, and reporting requirements/exceptions. To gather opinions on MISEV and ideas for new updates, the ISEV Board of Directors canvassed previous MISEV authors and society members. Here, we share conclusions that are relevant to the ongoing evolution of the MISEV initiative and other ISEV rigour and standardization efforts. John Wiley and Sons Inc. 2021-12-25 2021-12 /pmc/articles/PMC8710080/ /pubmed/34953156 http://dx.doi.org/10.1002/jev2.12182 Text en © 2021 The Authors. Journal of Extracellular Vesicles published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Editorial Witwer, Kenneth W Goberdhan, Deborah CI O'Driscoll, Lorraine Théry, Clotilde Welsh, Joshua A Blenkiron, Cherie Buzás, Edit I Di Vizio, Dolores Erdbrügger, Uta Falcón‐Pérez, Juan M Fu, Qing‐Ling Hill, Andrew F Lenassi, Metka Lötvall, Jan Nieuwland, Rienk Ochiya, Takahiro Rome, Sophie Sahoo, Susmita Zheng, Lei Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles |
title | Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles |
title_full | Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles |
title_fullStr | Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles |
title_full_unstemmed | Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles |
title_short | Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles |
title_sort | updating misev: evolving the minimal requirements for studies of extracellular vesicles |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710080/ https://www.ncbi.nlm.nih.gov/pubmed/34953156 http://dx.doi.org/10.1002/jev2.12182 |
work_keys_str_mv | AT witwerkennethw updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT goberdhandeborahci updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT odriscolllorraine updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT theryclotilde updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT welshjoshuaa updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT blenkironcherie updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT buzasediti updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT diviziodolores updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT erdbruggeruta updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT falconperezjuanm updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT fuqingling updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT hillandrewf updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT lenassimetka updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT lotvalljan updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT nieuwlandrienk updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT ochiyatakahiro updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT romesophie updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT sahoosusmita updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles AT zhenglei updatingmisevevolvingtheminimalrequirementsforstudiesofextracellularvesicles |