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Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries

Growth faltering under 5 years of age is unacceptably high worldwide, and even more children, while not stunted, fail to reach their growth potential. The time between conception and 2 years of age is critical for development. The period from 6 to 23 months, when complementary foods are introduced,...

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Autores principales: Parikh, Panam, Semba, Richard, Manary, Mark, Swaminathan, Sumathi, Udomkesmalee, Emorn, Bos, Rolf, Poh, Bee Koon, Rojroongwasinkul, Nipa, Geurts, Jan, Sekartini, Rini, Nga, Tran Thuy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710096/
https://www.ncbi.nlm.nih.gov/pubmed/34467645
http://dx.doi.org/10.1111/mcn.13264
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author Parikh, Panam
Semba, Richard
Manary, Mark
Swaminathan, Sumathi
Udomkesmalee, Emorn
Bos, Rolf
Poh, Bee Koon
Rojroongwasinkul, Nipa
Geurts, Jan
Sekartini, Rini
Nga, Tran Thuy
author_facet Parikh, Panam
Semba, Richard
Manary, Mark
Swaminathan, Sumathi
Udomkesmalee, Emorn
Bos, Rolf
Poh, Bee Koon
Rojroongwasinkul, Nipa
Geurts, Jan
Sekartini, Rini
Nga, Tran Thuy
author_sort Parikh, Panam
collection PubMed
description Growth faltering under 5 years of age is unacceptably high worldwide, and even more children, while not stunted, fail to reach their growth potential. The time between conception and 2 years of age is critical for development. The period from 6 to 23 months, when complementary foods are introduced, coincides with a time when growth faltering and delayed neurocognitive developments are most common. Fortunately, this is also the period when diet exercises its greatest influence. Growing up in an adverse environment, with a deficient diet, as typically seen in low‐ and middle‐income countries (LMICs), hampers growth and development of children and prevents them from realising their full developmental and economic future potential. Sufficient nutrient availability and utilisation are paramount to a child's growth and development trajectory, especially in the period after breastfeeding. This review highlights the importance of essential amino acids (EAAs) in early life for linear growth and, likely, neurocognitive development. The paper further discusses signalling through mammalian target of rapamycin complex 1 (mTORC1) as one of the main amino acid (AA)‐sensing hubs and the master regulator of both growth and neurocognitive development. Children in LMICs, despite consuming sufficient total protein, do not meet their EAA requirements due to poor diet diversity and low‐quality dietary protein. AA deficiencies in early life can cause reductions in linear growth and cognition. Ensuring AA adequacy in diets, particularly through inclusion of nutrient‐dense animal source foods from 6 to 23 months, is strongly encouraged in LMICs in order to compensate for less than optimal growth during complementary feeding.
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spelling pubmed-87100962022-01-04 Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries Parikh, Panam Semba, Richard Manary, Mark Swaminathan, Sumathi Udomkesmalee, Emorn Bos, Rolf Poh, Bee Koon Rojroongwasinkul, Nipa Geurts, Jan Sekartini, Rini Nga, Tran Thuy Matern Child Nutr Review Articles Growth faltering under 5 years of age is unacceptably high worldwide, and even more children, while not stunted, fail to reach their growth potential. The time between conception and 2 years of age is critical for development. The period from 6 to 23 months, when complementary foods are introduced, coincides with a time when growth faltering and delayed neurocognitive developments are most common. Fortunately, this is also the period when diet exercises its greatest influence. Growing up in an adverse environment, with a deficient diet, as typically seen in low‐ and middle‐income countries (LMICs), hampers growth and development of children and prevents them from realising their full developmental and economic future potential. Sufficient nutrient availability and utilisation are paramount to a child's growth and development trajectory, especially in the period after breastfeeding. This review highlights the importance of essential amino acids (EAAs) in early life for linear growth and, likely, neurocognitive development. The paper further discusses signalling through mammalian target of rapamycin complex 1 (mTORC1) as one of the main amino acid (AA)‐sensing hubs and the master regulator of both growth and neurocognitive development. Children in LMICs, despite consuming sufficient total protein, do not meet their EAA requirements due to poor diet diversity and low‐quality dietary protein. AA deficiencies in early life can cause reductions in linear growth and cognition. Ensuring AA adequacy in diets, particularly through inclusion of nutrient‐dense animal source foods from 6 to 23 months, is strongly encouraged in LMICs in order to compensate for less than optimal growth during complementary feeding. John Wiley and Sons Inc. 2021-08-31 /pmc/articles/PMC8710096/ /pubmed/34467645 http://dx.doi.org/10.1111/mcn.13264 Text en © 2021 FrieslandCampina. Maternal & Child Nutrition published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review Articles
Parikh, Panam
Semba, Richard
Manary, Mark
Swaminathan, Sumathi
Udomkesmalee, Emorn
Bos, Rolf
Poh, Bee Koon
Rojroongwasinkul, Nipa
Geurts, Jan
Sekartini, Rini
Nga, Tran Thuy
Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries
title Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries
title_full Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries
title_fullStr Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries
title_full_unstemmed Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries
title_short Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries
title_sort animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710096/
https://www.ncbi.nlm.nih.gov/pubmed/34467645
http://dx.doi.org/10.1111/mcn.13264
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