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Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710296/ https://www.ncbi.nlm.nih.gov/pubmed/34954893 http://dx.doi.org/10.1002/ctm2.646 |
| _version_ | 1784623121410555904 |
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| author | El‐Battrawy, Ibrahim Lan, Huan Cyganek, Lukas Maywald, Lasse Zhong, Rujia Zhang, Feng Xu, Qiang Lee, Jihyun Duperrex, Eliane Hierlemann, Andreas Saguner, Ardan M. Duru, Firat Kovacs, Boldizsar Huang, Mengying Liao, Zhenxing Albers, Sebastian Müller, Jonas Dinkel, Hendrik Rose, Lena Hohn, Alyssa Yang, Zhen Qiao, Lin Li, Yingrui Lang, Siegfried Kleinsorge, Mandy Mügge, Andreas Aweimer, Assem Fan, Xuehui Diecke, Sebastian Akin, Ibrahim Li, Guang Zhou, Xiaobo |
| author_facet | El‐Battrawy, Ibrahim Lan, Huan Cyganek, Lukas Maywald, Lasse Zhong, Rujia Zhang, Feng Xu, Qiang Lee, Jihyun Duperrex, Eliane Hierlemann, Andreas Saguner, Ardan M. Duru, Firat Kovacs, Boldizsar Huang, Mengying Liao, Zhenxing Albers, Sebastian Müller, Jonas Dinkel, Hendrik Rose, Lena Hohn, Alyssa Yang, Zhen Qiao, Lin Li, Yingrui Lang, Siegfried Kleinsorge, Mandy Mügge, Andreas Aweimer, Assem Fan, Xuehui Diecke, Sebastian Akin, Ibrahim Li, Guang Zhou, Xiaobo |
| author_sort | El‐Battrawy, Ibrahim |
| collection | PubMed |
| description | |
| format | Online Article Text |
| id | pubmed-8710296 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-87102962021-12-27 Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening El‐Battrawy, Ibrahim Lan, Huan Cyganek, Lukas Maywald, Lasse Zhong, Rujia Zhang, Feng Xu, Qiang Lee, Jihyun Duperrex, Eliane Hierlemann, Andreas Saguner, Ardan M. Duru, Firat Kovacs, Boldizsar Huang, Mengying Liao, Zhenxing Albers, Sebastian Müller, Jonas Dinkel, Hendrik Rose, Lena Hohn, Alyssa Yang, Zhen Qiao, Lin Li, Yingrui Lang, Siegfried Kleinsorge, Mandy Mügge, Andreas Aweimer, Assem Fan, Xuehui Diecke, Sebastian Akin, Ibrahim Li, Guang Zhou, Xiaobo Clin Transl Med Letter to Editor John Wiley and Sons Inc. 2021-12-26 /pmc/articles/PMC8710296/ /pubmed/34954893 http://dx.doi.org/10.1002/ctm2.646 Text en © 2021 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Letter to Editor El‐Battrawy, Ibrahim Lan, Huan Cyganek, Lukas Maywald, Lasse Zhong, Rujia Zhang, Feng Xu, Qiang Lee, Jihyun Duperrex, Eliane Hierlemann, Andreas Saguner, Ardan M. Duru, Firat Kovacs, Boldizsar Huang, Mengying Liao, Zhenxing Albers, Sebastian Müller, Jonas Dinkel, Hendrik Rose, Lena Hohn, Alyssa Yang, Zhen Qiao, Lin Li, Yingrui Lang, Siegfried Kleinsorge, Mandy Mügge, Andreas Aweimer, Assem Fan, Xuehui Diecke, Sebastian Akin, Ibrahim Li, Guang Zhou, Xiaobo Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening |
| title | Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening |
| title_full | Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening |
| title_fullStr | Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening |
| title_full_unstemmed | Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening |
| title_short | Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening |
| title_sort | deciphering the pathogenic role of a variant with uncertain significance for short qt and brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening |
| topic | Letter to Editor |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710296/ https://www.ncbi.nlm.nih.gov/pubmed/34954893 http://dx.doi.org/10.1002/ctm2.646 |
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