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Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure

A 56-year-old woman presenting with type II respiratory failure was transferred to our hospital. She did not exhibit muscle weakness or elevated serum myogenic enzymes, but needle electromyography revealed myogenic changes in the limb muscles, and her blood tests were positive for anti-mitochondrial...

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Autores principales: Fujii, Shintaro, Horiuchi, Kazuhiro, Oshima, Yuki, Eguchi, Katsuki, Nagai, Azusa, Iwata, Ikuko, Matsushima, Masaaki, Yabe, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710372/
https://www.ncbi.nlm.nih.gov/pubmed/34092736
http://dx.doi.org/10.2169/internalmedicine.7448-21
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author Fujii, Shintaro
Horiuchi, Kazuhiro
Oshima, Yuki
Eguchi, Katsuki
Nagai, Azusa
Iwata, Ikuko
Matsushima, Masaaki
Yabe, Ichiro
author_facet Fujii, Shintaro
Horiuchi, Kazuhiro
Oshima, Yuki
Eguchi, Katsuki
Nagai, Azusa
Iwata, Ikuko
Matsushima, Masaaki
Yabe, Ichiro
author_sort Fujii, Shintaro
collection PubMed
description A 56-year-old woman presenting with type II respiratory failure was transferred to our hospital. She did not exhibit muscle weakness or elevated serum myogenic enzymes, but needle electromyography revealed myogenic changes in the limb muscles, and her blood tests were positive for anti-mitochondrial antibodies (AMA). Muscle histopathological findings included immune-mediated necrotizing myopathy, so she was diagnosed with inflammatory myopathy associated with AMA. After treatment with corticosteroids and noninvasive positive pressure ventilation, her symptoms improved. If a diagnosis of type II respiratory failure is difficult, inflammatory myopathy associated with AMA should be considered as a differential diagnosis.
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spelling pubmed-87103722022-01-25 Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure Fujii, Shintaro Horiuchi, Kazuhiro Oshima, Yuki Eguchi, Katsuki Nagai, Azusa Iwata, Ikuko Matsushima, Masaaki Yabe, Ichiro Intern Med Case Report A 56-year-old woman presenting with type II respiratory failure was transferred to our hospital. She did not exhibit muscle weakness or elevated serum myogenic enzymes, but needle electromyography revealed myogenic changes in the limb muscles, and her blood tests were positive for anti-mitochondrial antibodies (AMA). Muscle histopathological findings included immune-mediated necrotizing myopathy, so she was diagnosed with inflammatory myopathy associated with AMA. After treatment with corticosteroids and noninvasive positive pressure ventilation, her symptoms improved. If a diagnosis of type II respiratory failure is difficult, inflammatory myopathy associated with AMA should be considered as a differential diagnosis. The Japanese Society of Internal Medicine 2021-06-05 2021-12-01 /pmc/articles/PMC8710372/ /pubmed/34092736 http://dx.doi.org/10.2169/internalmedicine.7448-21 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fujii, Shintaro
Horiuchi, Kazuhiro
Oshima, Yuki
Eguchi, Katsuki
Nagai, Azusa
Iwata, Ikuko
Matsushima, Masaaki
Yabe, Ichiro
Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
title Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
title_full Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
title_fullStr Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
title_full_unstemmed Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
title_short Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
title_sort inflammatory myopathy associated with anti-mitochondrial antibody presenting only with respiratory failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710372/
https://www.ncbi.nlm.nih.gov/pubmed/34092736
http://dx.doi.org/10.2169/internalmedicine.7448-21
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