Endogenous Oleoylethanolamide Crystals Loaded Lipid Nanoparticles with Enhanced Hydrophobic Drug Loading Capacity for Efficient Stroke Therapy

INTRODUCTION: Although the preparation of lipid nanoparticles (LNPs) achieves great success, their retention of highly hydrophobic drugs is still problematic. METHODS: Herein, we report a novel strategy for efficiently loading hydrophobic drugs to LNPs for stroke therapy. Oleoylethanolamide (OEA), a...

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Detalles Bibliográficos
Autores principales: Wu, Shichao, Liao, Di, Li, Xi, Liu, Zeyu, Zhang, Lin, Mo, Fong Ming, Hu, Shuo, Xia, Jian, Yang, Xiangrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710526/
https://www.ncbi.nlm.nih.gov/pubmed/34992362
http://dx.doi.org/10.2147/IJN.S344318

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