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FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin

KLF15 is a transcription factor that plays an important role in the activation of gluconeogenesis from amino acids as well as the suppression of lipogenesis from glucose. Here we identified the transcription start site of liver-specific KLF15 transcript and showed that FoxO1/3 transcriptionally regu...

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Detalles Bibliográficos
Autores principales: Takeuchi, Yoshinori, Yahagi, Naoya, Aita, Yuichi, Mehrazad-Saber, Zahra, Ho, Man Hei, Huyan, Yiren, Murayama, Yuki, Shikama, Akito, Masuda, Yukari, Izumida, Yoshihiko, Miyamoto, Takafumi, Matsuzaka, Takashi, Kawakami, Yasushi, Shimano, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710527/
https://www.ncbi.nlm.nih.gov/pubmed/34988390
http://dx.doi.org/10.1016/j.isci.2021.103446