Cargando…

Siglec Signaling in the Tumor Microenvironment

Sialic acid-binding immunoglobulin-like lectins (Siglecs) are a family of receptors that recognize sialoglycans – sialic acid containing glycans that are abundantly present on cell membranes. Siglecs are expressed on most immune cells and can modulate their activity and function. The majority of Sig...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Houtum, Eline J. H., Büll, Christian, Cornelissen, Lenneke A. M., Adema, Gosse J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710542/ https://www.ncbi.nlm.nih.gov/pubmed/34966391 http://dx.doi.org/10.3389/fimmu.2021.790317

Ejemplares similares

Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7
por: van Houtum, Eline J. H., et al.
Publicado: (2023)

Immune Modulation Plus Tumor Ablation: Adjuvants and Antibodies to Prime and Boost Anti-Tumor Immunity In Situ
por: van den Bijgaart, Renske J. E., et al.
Publicado: (2021)

Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma
por: Santegoets, Kim C. M., et al.
Publicado: (2019)

B Cell Siglecs–News on Signaling and Its Interplay With Ligand Binding
por: Meyer, Sarah J., et al.
Publicado: (2018)

Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma
por: Chen, Quan, et al.
Publicado: (2023)

The intriguing roles of Siglec family members in the tumor microenvironment
por: Jiang, Kui-Ying, et al.
Publicado: (2022)

Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro
por: Carroll, Daniela J., et al.
Publicado: (2021)

The Role of Siglec-G on Immune Cells in Sepsis
por: Royster, William, et al.
Publicado: (2021)

CD24-Siglec interactions in inflammatory diseases
por: Liu, Yang, et al.
Publicado: (2023)

Modulation of Immune Tolerance via Siglec-Sialic Acid Interactions
por: Lübbers, Joyce, et al.
Publicado: (2018)

Molecular Mechanism of Tumor Cell Immune Escape Mediated by CD24/Siglec-10
por: Yin, Shan-Shan, et al.
Publicado: (2020)

Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells
por: Lustig, Marta, et al.
Publicado: (2023)

PD-L1 Antibody Pharmacokinetics and Tumor Targeting in Mouse Models for Infectious Diseases
por: Sandker, Gerwin G. W., et al.
Publicado: (2022)

Recent Progress in the Methodologies to Identify Physiological Ligands of Siglecs
por: Jiang, Huei-Syuan, et al.
Publicado: (2021)

The Inflammatory Role of Platelets via Their TLRs and Siglec Receptors
por: Cognasse, Fabrice, et al.
Publicado: (2015)

MUC1 modulates the tumor immune microenvironment through the engagement of Siglec-9
por: Beatson, Richard, et al.
Publicado: (2016)

Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs
por: Angata, Takashi
Publicado: (2018)

Multi-omics analysis of Siglec family genes in cutaneous melanoma
por: Li, Kezhu, et al.
Publicado: (2023)

Adjuvants Enhancing Cross-Presentation by Dendritic Cells: The Key to More Effective Vaccines?
por: Ho, Nataschja I., et al.
Publicado: (2018)

Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells
por: Yu, Yingxin, et al.
Publicado: (2018)

Mechanical high-intensity focused ultrasound creates unique tumor debris enhancing dendritic cell-induced T cell activation
por: van den Bijgaart, Renske J. E., et al.
Publicado: (2022)

Siglec15 is a prognostic indicator and a potential tumor-related macrophage regulator that is involved in the suppressive immunomicroenvironment in gliomas
por: Wang, Jinchao, et al.
Publicado: (2023)

Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis
por: Lamprinaki, Dimitra, et al.
Publicado: (2021)

The Emerging Role of CD244 Signaling in Immune Cells of the Tumor Microenvironment
por: Agresta, Laura, et al.
Publicado: (2018)

The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation
por: Korver, Wouter, et al.
Publicado: (2022)

Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV)
por: Xie, Jiexiong, et al.
Publicado: (2017)

Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
por: Rodriguez, Ernesto, et al.
Publicado: (2021)

Dendritic Cells From the Cervical Mucosa Capture and Transfer HIV-1 via Siglec-1
por: Perez-Zsolt, Daniel, et al.
Publicado: (2019)

Siglecs Modulate Activities of Immune Cells Through Positive and Negative Regulation of ROS Generation
por: Karmakar, Joyshree, et al.
Publicado: (2021)

Unveiling the molecular features, relevant immune and clinical characteristics of SIGLEC15 in thyroid cancer
por: Hou, Xiaofeng, et al.
Publicado: (2022)

An Altered gp100 Peptide Ligand with Decreased Binding by TCR and CD8α Dissects T Cell Cytotoxicity from Production of Cytokines and Activation of NFAT
por: Schaft, Niels, et al.
Publicado: (2013)

Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents
por: Kroesen, Michiel, et al.
Publicado: (2015)

Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9
por: Chan, Chilam, et al.
Publicado: (2023)

Retroviruses As Myeloid Cell Riders: What Natural Human Siglec-1 “Knockouts” Tell Us About Pathogenesis
por: Martinez-Picado, Javier, et al.
Publicado: (2017)

Regulation of B Cell Functions by the Sialic Acid-Binding Receptors Siglec-G and CD22
por: Jellusova, Julia, et al.
Publicado: (2012)

Decreased Siglec-9 Expression on Natural Killer Cell Subset Associated With Persistent HBV Replication
por: Zhao, Di, et al.
Publicado: (2018)

Host Immune Responses in HIV-1 Infection: The Emerging Pathogenic Role of Siglecs and Their Clinical Correlates
por: Mikulak, Joanna, et al.
Publicado: (2017)

Molecular Basis and Role of Siglec-7 Ligand Expression on Chronic Lymphocytic Leukemia B Cells
por: Chang, Lan-Yi, et al.
Publicado: (2022)

Tumor Derived SIGLEC Family Genes May Play Roles in Tumor Genesis, Progression, and Immune Microenvironment Regulation
por: Chen, Zheng, et al.
Publicado: (2020)

Siglec-H-Deficient Mice Show Enhanced Type I IFN Responses, but Do Not Develop Autoimmunity After Influenza or LCMV Infections
por: Szumilas, Nadine, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rnuf6u13efbj25lrslhr9is482