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Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development

Brain development is a highly orchestrated process requiring spatiotemporally regulated mitochondrial dynamics. Drp1, a key molecule in the mitochondrial fission machinery, undergoes various post-translational modifications including conjugation to the small ubiquitin-like modifier (SUMO). However,...

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Detalles Bibliográficos
Autores principales:	Yamada, Seiya, Sato, Ayaka, Ishihara, Naotada, Akiyama, Hiroki, Sakakibara, Shin-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710555/ https://www.ncbi.nlm.nih.gov/pubmed/34988397 http://dx.doi.org/10.1016/j.isci.2021.103484

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