Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review

Angiographically silent cystoid macular edema (CME) is a rare complication from nab-paclitaxel. Here we report a 45-year-old woman with breast cancer who developed CME after several months of treatment with albumin-bound paclitaxel (nab-paclitaxel). Her visual acuity did not improve significantly wi...

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Autores principales: Ye, Suna, Fang, Qiqi, Yao, Jinyu, Xing, Jianqiang, Tang, Shibo, Ma, Jacey Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710691/
https://www.ncbi.nlm.nih.gov/pubmed/34966680
http://dx.doi.org/10.3389/fonc.2021.773540
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author Ye, Suna
Fang, Qiqi
Yao, Jinyu
Xing, Jianqiang
Tang, Shibo
Ma, Jacey Hongjie
author_facet Ye, Suna
Fang, Qiqi
Yao, Jinyu
Xing, Jianqiang
Tang, Shibo
Ma, Jacey Hongjie
author_sort Ye, Suna
collection PubMed
description Angiographically silent cystoid macular edema (CME) is a rare complication from nab-paclitaxel. Here we report a 45-year-old woman with breast cancer who developed CME after several months of treatment with albumin-bound paclitaxel (nab-paclitaxel). Her visual acuity did not improve significantly with the cessation of nab-paclitaxel and intravitreal ranibizumab treatment. Then, brinzolamide eye drops were prescribed. One month later, her vision improved, with the macular edema significantly subsided. Finally, we reviewed other cases of CME induced by nab-paclitaxel that have been reported in the literature and discussed the underlying pathogenesis of nab-paclitaxel-induced CME.
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spelling pubmed-87106912021-12-28 Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review Ye, Suna Fang, Qiqi Yao, Jinyu Xing, Jianqiang Tang, Shibo Ma, Jacey Hongjie Front Oncol Oncology Angiographically silent cystoid macular edema (CME) is a rare complication from nab-paclitaxel. Here we report a 45-year-old woman with breast cancer who developed CME after several months of treatment with albumin-bound paclitaxel (nab-paclitaxel). Her visual acuity did not improve significantly with the cessation of nab-paclitaxel and intravitreal ranibizumab treatment. Then, brinzolamide eye drops were prescribed. One month later, her vision improved, with the macular edema significantly subsided. Finally, we reviewed other cases of CME induced by nab-paclitaxel that have been reported in the literature and discussed the underlying pathogenesis of nab-paclitaxel-induced CME. Frontiers Media S.A. 2021-12-13 /pmc/articles/PMC8710691/ /pubmed/34966680 http://dx.doi.org/10.3389/fonc.2021.773540 Text en Copyright © 2021 Ye, Fang, Yao, Xing, Tang and Ma https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Ye, Suna
Fang, Qiqi
Yao, Jinyu
Xing, Jianqiang
Tang, Shibo
Ma, Jacey Hongjie
Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review
title Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review
title_full Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review
title_fullStr Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review
title_full_unstemmed Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review
title_short Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review
title_sort intravitreal ranibizumab had limited effect on cystoid macular edema due to albumin-bound paclitaxel: a case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710691/
https://www.ncbi.nlm.nih.gov/pubmed/34966680
http://dx.doi.org/10.3389/fonc.2021.773540
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