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Rhubarb Enema Decreases Circulating Trimethylamine N-Oxide Level and Improves Renal Fibrosis Accompanied With Gut Microbiota Change in Chronic Kidney Disease Rats

Objectives: Trimethylamine N-oxide (TMAO), a metabolic product of gut flora, is increased in chronic kidney disease (CKD) subjects and is recognized as one type of uremic toxins which is associated with poor cardiovascular outcomes and kidney function loss. Previous studies have suggested that rhuba...

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Detalles Bibliográficos
Autores principales:	Ji, Chunlan, Li, Yin, Mo, Yenan, Lu, Zhaoyu, Lu, Fuhua, Lin, Qizhan, Liu, Xusheng, Zou, Chuan, Wu, Yuchi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710758/ https://www.ncbi.nlm.nih.gov/pubmed/34966280 http://dx.doi.org/10.3389/fphar.2021.780924

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