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The role of Mesothelin signaling in Portal Fibroblasts in the pathogenesis of cholestatic liver fibrosis

Liver fibrosis develops in response to chronic toxic or cholestatic injury, and is characterized by apoptosis of damaged hepatocytes, development of inflammatory responses, and activation of Collagen Type I producing myofibroblasts that make liver fibrotic. Two major cell types, Hepatic Stellate Cel...

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Detalles Bibliográficos
Autores principales: Fuji, Hiroaki, Miller, Grant, Nishio, Takahiro, Koyama, Yukinori, Lam, Kevin, Zhang, Vivian, Loomba, Rohit, Brenner, David, Kisseleva, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710774/
https://www.ncbi.nlm.nih.gov/pubmed/34966784
http://dx.doi.org/10.3389/fmolb.2021.790032

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