Transcriptomic Cross‐Species Analysis of Chronic Liver Disease Reveals Consistent Regulation Between Humans and Mice

Mouse models are frequently used to study chronic liver diseases (CLDs). To assess their translational relevance, we quantified the similarity of commonly used mouse models to human CLDs based on transcriptome data. Gene‐expression data from 372 patients were compared with data from acute and chroni...

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Detalles Bibliográficos
Autores principales: Holland, Christian H., Ramirez Flores, Ricardo O., Myllys, Maiju, Hassan, Reham, Edlund, Karolina, Hofmann, Ute, Marchan, Rosemarie, Cadenas, Cristina, Reinders, Jörg, Hoehme, Stefan, Seddek, Abdel‐latif, Dooley, Steven, Keitel, Verena, Godoy, Patricio, Begher‐Tibbe, Brigitte, Trautwein, Christian, Rupp, Christian, Mueller, Sebastian, Longerich, Thomas, Hengstler, Jan G., Saez‐Rodriguez, Julio, Ghallab, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710791/
https://www.ncbi.nlm.nih.gov/pubmed/34558834
http://dx.doi.org/10.1002/hep4.1797

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