Single-cell transcriptomics reveals lasting changes in the lung cellular landscape into adulthood after neonatal hyperoxic exposure

Ventilatory support, such as supplemental oxygen, used to save premature infants impairs the growth of the pulmonary microvasculature and distal alveoli, leading to bronchopulmonary dysplasia (BPD). Although lung cellular composition changes with exposure to hyperoxia in neonatal mice, most human BP...

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Detalles Bibliográficos
Autores principales: Scaffa, Alejandro, Yao, Hongwei, Oulhen, Nathalie, Wallace, Joselynn, Peterson, Abigail L., Rizal, Salu, Ragavendran, Ashok, Wessel, Gary, De Paepe, Monique E., Dennery, Phyllis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Articles from the Special Issue on Redox signaling in the pathogenesis and treatments of acute lung injury and beyond; Edited by Dr. Lin Mantell, Dr. Peter Vitiello and Dr. Eva Nozik
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710996/
https://www.ncbi.nlm.nih.gov/pubmed/34417156
http://dx.doi.org/10.1016/j.redox.2021.102091

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