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Safety and Tolerability of Intravitreal Carotuximab (DE-122) in Patients With Persistent Exudative Age-Related Macular Degeneration: A Phase I Study
PURPOSE: Carotuximab (DE-122) is a novel endoglin antibody that exhibits potent anti-angiogenic activity. The aim of this study was to evaluate the safety and tolerability of a single intravitreal injection of four ascending doses of carotuximab in patients with persistent exudative age-related macu...
Autores principales: | Gonzalez, Victor H., Berger, Brian, Goldberg, Roger, Gordon, Carmelina M., Khurana, Rahul N., Angeles, Raymund, Shams, Naveed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711001/ https://www.ncbi.nlm.nih.gov/pubmed/34935908 http://dx.doi.org/10.1167/tvst.10.14.27 |
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