Targeting PLD2 in adipocytes augments adaptive thermogenesis by improving mitochondrial quality and quantity in mice

Phospholipase D (PLD)2 via its enzymatic activity regulates cell proliferation and migration and thus is implicated in cancer. However, the role of PLD2 in obesity and type 2 diabetes has not previously been investigated. Here, we show that during diet-induced thermogenesis and obesity, levels of PL...

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Detalles Bibliográficos
Autores principales: Kim, Hyung Sik, Park, Min Young, Yun, Nam Joo, Go, Hye Sun, Kim, Mi Young, Seong, Je Kyung, Lee, Minyoung, Kang, Eun Seok, Ghim, Jaewang, Ryu, Sung Ho, Zabel, Brian A., Koh, Ara, Bae, Yoe-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711045/
https://www.ncbi.nlm.nih.gov/pubmed/34940790
http://dx.doi.org/10.1084/jem.20211523

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