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Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data
The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711049/ https://www.ncbi.nlm.nih.gov/pubmed/34988269 http://dx.doi.org/10.1016/j.dib.2021.107634 |
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author | Eggenberger, Samuel C. James, Natalie L. Ho, Cherry Eamegdool, Steven S. Tatarinoff, Veronika Craig, Naomi A. Gow, Barry S. Wan, Susan Dodds, Christopher W.D. La Hood, Donna Gilmour, Aaron Donahoe, Shannon L. Krockenberger, Mark Tumuluri, Krishna da Cruz, Melville J. Grigg, John R. McCluskey, Peter Lovell, Nigel H. Madigan, Michele C. Fung, Adrian T. Suaning, Gregg J. |
author_facet | Eggenberger, Samuel C. James, Natalie L. Ho, Cherry Eamegdool, Steven S. Tatarinoff, Veronika Craig, Naomi A. Gow, Barry S. Wan, Susan Dodds, Christopher W.D. La Hood, Donna Gilmour, Aaron Donahoe, Shannon L. Krockenberger, Mark Tumuluri, Krishna da Cruz, Melville J. Grigg, John R. McCluskey, Peter Lovell, Nigel H. Madigan, Michele C. Fung, Adrian T. Suaning, Gregg J. |
author_sort | Eggenberger, Samuel C. |
collection | PubMed |
description | The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with an electrically inactive, suprachoroidal retinal stimulator (Bionic Eye) for durations of up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed. Intraocular pressure measurements, indirect and infrared ophthalmoscopy and optical coherence tomography were performed at fixed time points to evaluate the clinical effects of the surgery and device implantation. Post-mortem eye tissue collection and histology was performed to measure the effects of the intervention at the cellular level. The data, including a comprehensive collection of fundus, infrared, optical coherence tomography and histology images can be used as a reference for comparison with other research, for example, active retinal stimulators. Furthermore, these data can be used to evaluate the suitability of the sheep model, in particular Dorper sheep, for future research. |
format | Online Article Text |
id | pubmed-8711049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-87110492022-01-04 Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data Eggenberger, Samuel C. James, Natalie L. Ho, Cherry Eamegdool, Steven S. Tatarinoff, Veronika Craig, Naomi A. Gow, Barry S. Wan, Susan Dodds, Christopher W.D. La Hood, Donna Gilmour, Aaron Donahoe, Shannon L. Krockenberger, Mark Tumuluri, Krishna da Cruz, Melville J. Grigg, John R. McCluskey, Peter Lovell, Nigel H. Madigan, Michele C. Fung, Adrian T. Suaning, Gregg J. Data Brief Data Article The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with an electrically inactive, suprachoroidal retinal stimulator (Bionic Eye) for durations of up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed. Intraocular pressure measurements, indirect and infrared ophthalmoscopy and optical coherence tomography were performed at fixed time points to evaluate the clinical effects of the surgery and device implantation. Post-mortem eye tissue collection and histology was performed to measure the effects of the intervention at the cellular level. The data, including a comprehensive collection of fundus, infrared, optical coherence tomography and histology images can be used as a reference for comparison with other research, for example, active retinal stimulators. Furthermore, these data can be used to evaluate the suitability of the sheep model, in particular Dorper sheep, for future research. Elsevier 2021-11-26 /pmc/articles/PMC8711049/ /pubmed/34988269 http://dx.doi.org/10.1016/j.dib.2021.107634 Text en © 2021 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Eggenberger, Samuel C. James, Natalie L. Ho, Cherry Eamegdool, Steven S. Tatarinoff, Veronika Craig, Naomi A. Gow, Barry S. Wan, Susan Dodds, Christopher W.D. La Hood, Donna Gilmour, Aaron Donahoe, Shannon L. Krockenberger, Mark Tumuluri, Krishna da Cruz, Melville J. Grigg, John R. McCluskey, Peter Lovell, Nigel H. Madigan, Michele C. Fung, Adrian T. Suaning, Gregg J. Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data |
title | Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data |
title_full | Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data |
title_fullStr | Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data |
title_full_unstemmed | Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data |
title_short | Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data |
title_sort | safety and biocompatibility of a bionic eye: imaging, intraocular pressure, and histology data |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711049/ https://www.ncbi.nlm.nih.gov/pubmed/34988269 http://dx.doi.org/10.1016/j.dib.2021.107634 |
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