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Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data

The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7...

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Autores principales: Eggenberger, Samuel C., James, Natalie L., Ho, Cherry, Eamegdool, Steven S., Tatarinoff, Veronika, Craig, Naomi A., Gow, Barry S., Wan, Susan, Dodds, Christopher W.D., La Hood, Donna, Gilmour, Aaron, Donahoe, Shannon L., Krockenberger, Mark, Tumuluri, Krishna, da Cruz, Melville J., Grigg, John R., McCluskey, Peter, Lovell, Nigel H., Madigan, Michele C., Fung, Adrian T., Suaning, Gregg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711049/
https://www.ncbi.nlm.nih.gov/pubmed/34988269
http://dx.doi.org/10.1016/j.dib.2021.107634
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author Eggenberger, Samuel C.
James, Natalie L.
Ho, Cherry
Eamegdool, Steven S.
Tatarinoff, Veronika
Craig, Naomi A.
Gow, Barry S.
Wan, Susan
Dodds, Christopher W.D.
La Hood, Donna
Gilmour, Aaron
Donahoe, Shannon L.
Krockenberger, Mark
Tumuluri, Krishna
da Cruz, Melville J.
Grigg, John R.
McCluskey, Peter
Lovell, Nigel H.
Madigan, Michele C.
Fung, Adrian T.
Suaning, Gregg J.
author_facet Eggenberger, Samuel C.
James, Natalie L.
Ho, Cherry
Eamegdool, Steven S.
Tatarinoff, Veronika
Craig, Naomi A.
Gow, Barry S.
Wan, Susan
Dodds, Christopher W.D.
La Hood, Donna
Gilmour, Aaron
Donahoe, Shannon L.
Krockenberger, Mark
Tumuluri, Krishna
da Cruz, Melville J.
Grigg, John R.
McCluskey, Peter
Lovell, Nigel H.
Madigan, Michele C.
Fung, Adrian T.
Suaning, Gregg J.
author_sort Eggenberger, Samuel C.
collection PubMed
description The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with an electrically inactive, suprachoroidal retinal stimulator (Bionic Eye) for durations of up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed. Intraocular pressure measurements, indirect and infrared ophthalmoscopy and optical coherence tomography were performed at fixed time points to evaluate the clinical effects of the surgery and device implantation. Post-mortem eye tissue collection and histology was performed to measure the effects of the intervention at the cellular level. The data, including a comprehensive collection of fundus, infrared, optical coherence tomography and histology images can be used as a reference for comparison with other research, for example, active retinal stimulators. Furthermore, these data can be used to evaluate the suitability of the sheep model, in particular Dorper sheep, for future research.
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spelling pubmed-87110492022-01-04 Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data Eggenberger, Samuel C. James, Natalie L. Ho, Cherry Eamegdool, Steven S. Tatarinoff, Veronika Craig, Naomi A. Gow, Barry S. Wan, Susan Dodds, Christopher W.D. La Hood, Donna Gilmour, Aaron Donahoe, Shannon L. Krockenberger, Mark Tumuluri, Krishna da Cruz, Melville J. Grigg, John R. McCluskey, Peter Lovell, Nigel H. Madigan, Michele C. Fung, Adrian T. Suaning, Gregg J. Data Brief Data Article The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with an electrically inactive, suprachoroidal retinal stimulator (Bionic Eye) for durations of up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed. Intraocular pressure measurements, indirect and infrared ophthalmoscopy and optical coherence tomography were performed at fixed time points to evaluate the clinical effects of the surgery and device implantation. Post-mortem eye tissue collection and histology was performed to measure the effects of the intervention at the cellular level. The data, including a comprehensive collection of fundus, infrared, optical coherence tomography and histology images can be used as a reference for comparison with other research, for example, active retinal stimulators. Furthermore, these data can be used to evaluate the suitability of the sheep model, in particular Dorper sheep, for future research. Elsevier 2021-11-26 /pmc/articles/PMC8711049/ /pubmed/34988269 http://dx.doi.org/10.1016/j.dib.2021.107634 Text en © 2021 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Eggenberger, Samuel C.
James, Natalie L.
Ho, Cherry
Eamegdool, Steven S.
Tatarinoff, Veronika
Craig, Naomi A.
Gow, Barry S.
Wan, Susan
Dodds, Christopher W.D.
La Hood, Donna
Gilmour, Aaron
Donahoe, Shannon L.
Krockenberger, Mark
Tumuluri, Krishna
da Cruz, Melville J.
Grigg, John R.
McCluskey, Peter
Lovell, Nigel H.
Madigan, Michele C.
Fung, Adrian T.
Suaning, Gregg J.
Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data
title Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data
title_full Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data
title_fullStr Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data
title_full_unstemmed Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data
title_short Safety and biocompatibility of a bionic eye: Imaging, intraocular pressure, and histology data
title_sort safety and biocompatibility of a bionic eye: imaging, intraocular pressure, and histology data
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711049/
https://www.ncbi.nlm.nih.gov/pubmed/34988269
http://dx.doi.org/10.1016/j.dib.2021.107634
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