Cargando…

Citrullinated myelin induces microglial TNFα and inhibits endogenous repair in the cuprizone model of demyelination

BACKGROUND: Microglia are the primary phagocytes of the central nervous system and are responsible for removing damaged myelin following demyelination. Previous investigations exploring the consequences of myelin phagocytosis on microglial activation overlooked the biochemical modifications present...

Descripción completa

Detalles Bibliográficos
Autores principales:	Standiford, Miranda M., Grund, Ethan M., Howe, Charles L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711191/ https://www.ncbi.nlm.nih.gov/pubmed/34961522 http://dx.doi.org/10.1186/s12974-021-02360-3

Ejemplares similares

Dock3 protects myelin in the cuprizone model for demyelination
por: Namekata, K, et al.
Publicado: (2014)

Myelin Protection by Ursolic Acid in Cuprizone-Induced Demyelination in Mice
por: Honarvar, Fatemeh, et al.
Publicado: (2019)

Age Influences Microglial Activation After Cuprizone-Induced Demyelination
por: Klein, Barbara, et al.
Publicado: (2018)

Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
por: Zirngibl, Martin, et al.
Publicado: (2022)

ISGylation is induced in neurons by demyelination driving ISG15-dependent microglial activation
por: Clarkson, Benjamin D. S., et al.
Publicado: (2022)

Quetiapine Inhibits Microglial Activation by Neutralizing Abnormal STIM1-Mediated Intercellular Calcium Homeostasis and Promotes Myelin Repair in a Cuprizone-Induced Mouse Model of Demyelination
por: Wang, Hanzhi, et al.
Publicado: (2015)

GAS6 Enhances Repair Following Cuprizone-Induced Demyelination
por: Tsiperson, Vladislav, et al.
Publicado: (2010)

Gas6 Increases Myelination by Oligodendrocytes and Its Deficiency Delays Recovery following Cuprizone-Induced Demyelination
por: Binder, Michele D., et al.
Publicado: (2011)

Strain differences in cuprizone induced demyelination
por: Yu, Qili, et al.
Publicado: (2017)

Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model
por: Khodanovich, Marina Yu, et al.
Publicado: (2017)

Cuprizone Intoxication Results in Myelin Vacuole Formation
por: Joost, Sarah, et al.
Publicado: (2022)

TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination
por: Liu, Meiying, et al.
Publicado: (2018)

The Effect of Aerobic Training With the Consumption of Probiotics on the Myelination of Nerve Fibers in Cuprizone-induced Demyelination Mouse Model of Multiple Sclerosis
por: Sajedi, Donya, et al.
Publicado: (2023)

Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination
por: Wang, Yumeng, et al.
Publicado: (2023)

A New Model of Cuprizone-Mediated Demyelination/Remyelination
por: Sachs, Hilary H., et al.
Publicado: (2014)

Cuprizone does not induce CNS demyelination in nonhuman primates
por: Chen, Zhihong, et al.
Publicado: (2015)

An Alternative Cuprizone-Induced Demyelination and Remyelination Mouse Model
por: Zhen, Wei, et al.
Publicado: (2017)

Effect of Fasudil on remyelination following cuprizone‐induced demyelination
por: Wang, Jing, et al.
Publicado: (2019)

Ferroptosis: copper-iron connection in cuprizone-induced demyelination
por: Jhelum, Priya, et al.
Publicado: (2021)

Five Decades of Cuprizone, an Updated Model to Replicate Demyelinating Diseases
por: Vega-Riquer, Jose M., et al.
Publicado: (2019)

Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model
por: Gingele, Stefan, et al.
Publicado: (2020)

Effects of intraventricular methotrexate administration on Cuprizone-induced demyelination in mice
por: Mueller, Andre M., et al.
Publicado: (2013)

Cuprizone feed formulation influences the extent of demyelinating disease pathology
por: Toomey, Lillian M., et al.
Publicado: (2021)

Astrogliosis during acute and chronic cuprizone demyelination and implications for remyelination
por: Hibbits, Norah, et al.
Publicado: (2012)

Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model
por: Tagge, Ian, et al.
Publicado: (2016)

Thalamocortical-auditory network alterations following cuprizone‐induced demyelination
por: Ghaffarian, Nikoo, et al.
Publicado: (2016)

Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model
por: Berghoff, Stefan A., et al.
Publicado: (2017)

Clozapine administration enhanced functional recovery after cuprizone demyelination
por: Templeton, Nikki, et al.
Publicado: (2019)

Retraction: Effect of Fasudil on remyelination following cuprizone‐induced demyelination.
por: Wang, Jing, et al.
Publicado: (2020)

Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper
por: Morgan, Megan L., et al.
Publicado: (2022)

EGF-Coupled Gold Nanoparticles Increase the Expression of CNPase and the Myelin-Associated Proteins MAG, MOG, and MBP in the Septal Nucleus Demyelinated by Cuprizone
por: Lira-Diaz, Eduardo, et al.
Publicado: (2022)

Sex Differences in the Behavioural Aspects of the Cuprizone-Induced Demyelination Model in Mice
por: Paton, Kelly F., et al.
Publicado: (2022)

Cuprizone demyelination induces a unique inflammatory response in the subventricular zone
por: Hillis, James M., et al.
Publicado: (2016)

Dietary Vitamin D3 Supplements Reduce Demyelination in the Cuprizone Model
por: Wergeland, Stig, et al.
Publicado: (2011)

Effect of Sox10 on remyelination of the hippocampus in cuprizone‐induced demyelinated mice
por: Shao, Yu, et al.
Publicado: (2020)

Immunofluorescence assay for demyelination, remyelination, and proliferation in an acute cuprizone mouse model
por: Clawson, Elizabeth D., et al.
Publicado: (2023)

Endogenous Cell Repair of Chronic Demyelination
por: Armstrong, Regina C., et al.
Publicado: (2006)

Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra
por: Praet, Jelle, et al.
Publicado: (2015)

CNS Demyelination with TNF-α Blockers
por: Kemanetzoglou, Elissavet, et al.
Publicado: (2017)

Histological and Top-Down Proteomic Analyses of the Visual Pathway in the Cuprizone Demyelination Model
por: Almuslehi, Mohammed S. M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eqqg32cvg16bm79dmscd98bkid