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Citrullinated myelin induces microglial TNFα and inhibits endogenous repair in the cuprizone model of demyelination

BACKGROUND: Microglia are the primary phagocytes of the central nervous system and are responsible for removing damaged myelin following demyelination. Previous investigations exploring the consequences of myelin phagocytosis on microglial activation overlooked the biochemical modifications present...

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Detalles Bibliográficos
Autores principales:	Standiford, Miranda M., Grund, Ethan M., Howe, Charles L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711191/ https://www.ncbi.nlm.nih.gov/pubmed/34961522 http://dx.doi.org/10.1186/s12974-021-02360-3

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