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Klf5 establishes bi-potential cell fate by dual regulation of ICM and TE specification genes

Early blastomeres of mouse preimplantation embryos exhibit bi-potential cell fate, capable of generating both embryonic and extra-embryonic lineages in blastocysts. Here we identify three major two-cell-stage (2C)-specific endogenous retroviruses (ERVs) as the molecular hallmark of this bi-potential...

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Detalles Bibliográficos
Autores principales:	Kinisu, Martin, Choi, Yong Jin, Cattoglio, Claudia, Liu, Ke, de Bezieux, Hector Roux, Valbuena, Raeline, Pum, Nicole, Dudoit, Sandrine, Huang, Haiyan, Xuan, Zhenyu, Kim, Sang Yong, He, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711565/ https://www.ncbi.nlm.nih.gov/pubmed/34758315 http://dx.doi.org/10.1016/j.celrep.2021.109982

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