Cargando…

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells

The RAS protein activator like 2 (RASAL2) negatively regulates RAS proto-oncogene which is activated by high mutation rate in cancer. Thus, RASAL2 expression could potentially limit the function of RAS in prostate cancer (PCa). Genome-wide DNA methylation analysis demonstrated that RASAL2 is differe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tailor, Krishma, Paul, Joseph, Ghosh, Somiranjan, Kumari, Namita, Kwabi-Addo, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711570/ https://www.ncbi.nlm.nih.gov/pubmed/34966481 http://dx.doi.org/10.18632/oncotarget.28158

Ejemplares similares

Sex differences in saliva-based DNA methylation changes and environmental stressor in young African American adults
por: Saadatmand, Forough, et al.
Publicado: (2022)

Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer
por: Creighton, Chad J., et al.
Publicado: (2023)

miR-136 suppresses tumor invasion and metastasis by targeting RASAL2 in triple-negative breast cancer
por: YAN, MEISI, et al.
Publicado: (2016)

Overexpression of RASAL1 Indicates Poor Prognosis and Promotes Invasion of Ovarian Cancer
por: Chang, Rui-Xia, et al.
Publicado: (2019)

Hypermethylation of RASAL1: A Key for Renal Fibrosis
por: Mao, Yuanjie
Publicado: (2014)

RASAL2 Plays Inconsistent Roles in Different Cancers
por: Zhou, Bolun, et al.
Publicado: (2019)

Phosphorylated Rasal2 facilitates breast cancer progression
por: Wang, Xuan, et al.
Publicado: (2019)

The expression and function of RASAL2 in renal cell carcinoma angiogenesis
por: Hui, Ke, et al.
Publicado: (2018)

Rasal2, highlighting the importance of phosphorylation on function in tumour development
por: Galindo-Hernandez, Octavio
Publicado: (2020)

Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders
por: Zhu, Xiaoqiang, et al.
Publicado: (2017)

RASAL1 and ROS1 Gene Variants in Hereditary Breast Cancer
por: Isidori, Federica, et al.
Publicado: (2020)

Correlating blood-based DNA methylation markers and prostate cancer risk in African-American men
por: Moses-Fynn, Emmanuel, et al.
Publicado: (2018)

Identification of Novel Tumor Markers in Prostate, Colon and Breast Cancer by Unbiased Methylation Profiling
por: Chung, Woonbok, et al.
Publicado: (2008)

Identification of Novel Tumor Markers in Prostate, Colon and Breast Cancer by Unbiased Methylation Profiling
por: Chung, Woonbok, et al.
Publicado: (2008)

Suppressive effects of RASAL2 on renal cell carcinoma via SOX2/ERK/p38 MAPK pathway
por: Wang, Sen, et al.
Publicado: (2020)

The Ras GTPase-Activating Protein Rasal3 Supports Survival of Naive T Cells
por: Muro, Ryunosuke, et al.
Publicado: (2015)

RASAL3 Is a Putative RasGAP Modulating Inflammatory Response by Neutrophils
por: Saito, Suguru, et al.
Publicado: (2021)

In silico studies of piperazine derivatives as potent anti-proliferative agents against PC-3 prostate cancer cell lines
por: Ikwu, Fabian A., et al.
Publicado: (2020)

RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis
por: Huang, Yuting, et al.
Publicado: (2014)

RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis
por: Takata, Akemi, et al.
Publicado: (2017)

RASAL3 predicts overall survival and CD8+ T lymphocyte infiltration in lung adenocarcinoma
por: Liang, Mei, et al.
Publicado: (2022)

RASAL2 regulates the cell cycle and cyclin D1 expression through PI3K/AKT signalling in prostate tumorigenesis
por: Wang, Qi, et al.
Publicado: (2022)

miR-130b-5p promotes proliferation, migration and invasion of gastric cancer cells via targeting RASAL1
por: Chen, Hong, et al.
Publicado: (2018)

miR-654-3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non-small-cell lung cancer
por: Xiong, Jie, et al.
Publicado: (2021)

RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer
por: Koh, Siang-Boon, et al.
Publicado: (2021)

CD229 interacts with RASAL3 to activate RAS/ERK pathway in multiple myeloma proliferation
por: Lin, Zigen, et al.
Publicado: (2022)

DNA methylation and exposure to violence among African American young adult males
por: Saadatmand, Forough, et al.
Publicado: (2021)

RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway
por: Wang, Guangchuan, et al.
Publicado: (2019)

IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation
por: Zhang, Wenjuan, et al.
Publicado: (2019)

Correction for: CD229 interacts with RASAL3 to activate RAS/ERK pathway in multiple myeloma proliferation
por: Lin, Zigen, et al.
Publicado: (2023)

SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells
por: Yang, Liu, et al.
Publicado: (2018)

Constitutive and Inducible Expression of Invasion-related Factors in PC-3 Prostate Cancer Cells
por: Hwang, Young Sun, et al.
Publicado: (2015)

CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca(2+)
por: Liu, Qing, et al.
Publicado: (2005)

RASAL1 inhibits HepG2 cell growth via HIF-2α mediated gluconeogenesis
por: Meng, Fanhua, et al.
Publicado: (2017)

GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity
por: Thaker, Youg Raj, et al.
Publicado: (2019)

Danhong Injection Alleviates Cardiac Fibrosis via Preventing the Hypermethylation of Rasal1 and Rassf1 in TAC Mice
por: Li, Sinai, et al.
Publicado: (2020)

Long noncoding RNA DLEU2 affects the proliferative and invasive ability of colorectal cancer cells
por: He, Xiaoyun, et al.
Publicado: (2021)

Relationship between Tumor DNA Methylation Status and Patient Characteristics in African-American and European-American Women with Breast Cancer
por: Wang, Songping, et al.
Publicado: (2012)

Combined treatment of PC-3 cells with ultrasound and microbubbles suppresses invasion and migration
por: WEI, CONG, et al.
Publicado: (2014)

RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma
por: Yue, Yangyang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2b3ki10urtt2666huk8ngsopqj