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Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over

AIMS: The purpose was to compare operative treatment with a volar plate and nonoperative treatment of displaced distal radius fractures in patients aged 65 years and over in a cost-effectiveness analysis. METHODS: A cost-utility analysis was performed alongside a randomized controlled trial. A total...

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Autores principales: Hassellund, Sondre, Zolic-Karlsson, Zinajda, Williksen, John Håkon, Husby, Torstein, Madsen, Jan Erik, Frihagen, Frede
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711656/
https://www.ncbi.nlm.nih.gov/pubmed/34856811
http://dx.doi.org/10.1302/2633-1462.212.BJO-2021-0108.R1
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author Hassellund, Sondre
Zolic-Karlsson, Zinajda
Williksen, John Håkon
Husby, Torstein
Madsen, Jan Erik
Frihagen, Frede
author_facet Hassellund, Sondre
Zolic-Karlsson, Zinajda
Williksen, John Håkon
Husby, Torstein
Madsen, Jan Erik
Frihagen, Frede
author_sort Hassellund, Sondre
collection PubMed
description AIMS: The purpose was to compare operative treatment with a volar plate and nonoperative treatment of displaced distal radius fractures in patients aged 65 years and over in a cost-effectiveness analysis. METHODS: A cost-utility analysis was performed alongside a randomized controlled trial. A total of 50 patients were randomized to each group. We prospectively collected data on resource use during the first year post-fracture, and estimated costs of initial treatment, further operations, physiotherapy, home nursing, and production loss. Health-related quality of life was based on the Euro-QoL five-dimension, five-level (EQ-5D-5L) utility index, and quality-adjusted life-years (QALYs) were calculated. RESULTS: The mean QALYs were 0.05 higher in the operative group during the first 12 months (p = 0.260). The healthcare provider costs were €1,533 higher per patient in the operative group: €3,589 in the operative group and 2,056 in the nonoperative group. With a suggested willingness to pay of €27,500 per QALY there was a 45% chance for operative treatment to be cost-effective. For both groups, the main costs were related to the primary treatment. The primary surgery was the main driver of the difference between the groups. The costs related to loss of production were high in both groups, despite high rates of retirement. Retirement rate was unevenly distributed between the groups and was not included in the analysis. CONCLUSION: Surgical treatment was not cost-effective in patients aged 65 years and older compared to nonoperative treatment of displaced distal radius fractures in a healthcare perspective. Costs related to loss of production might change this in the future if the retirement age increases. Level of evidence: II Cite this article: Bone Jt Open 2021;2(12):1027–1034.
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spelling pubmed-87116562022-01-13 Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over Hassellund, Sondre Zolic-Karlsson, Zinajda Williksen, John Håkon Husby, Torstein Madsen, Jan Erik Frihagen, Frede Bone Jt Open Trauma AIMS: The purpose was to compare operative treatment with a volar plate and nonoperative treatment of displaced distal radius fractures in patients aged 65 years and over in a cost-effectiveness analysis. METHODS: A cost-utility analysis was performed alongside a randomized controlled trial. A total of 50 patients were randomized to each group. We prospectively collected data on resource use during the first year post-fracture, and estimated costs of initial treatment, further operations, physiotherapy, home nursing, and production loss. Health-related quality of life was based on the Euro-QoL five-dimension, five-level (EQ-5D-5L) utility index, and quality-adjusted life-years (QALYs) were calculated. RESULTS: The mean QALYs were 0.05 higher in the operative group during the first 12 months (p = 0.260). The healthcare provider costs were €1,533 higher per patient in the operative group: €3,589 in the operative group and 2,056 in the nonoperative group. With a suggested willingness to pay of €27,500 per QALY there was a 45% chance for operative treatment to be cost-effective. For both groups, the main costs were related to the primary treatment. The primary surgery was the main driver of the difference between the groups. The costs related to loss of production were high in both groups, despite high rates of retirement. Retirement rate was unevenly distributed between the groups and was not included in the analysis. CONCLUSION: Surgical treatment was not cost-effective in patients aged 65 years and older compared to nonoperative treatment of displaced distal radius fractures in a healthcare perspective. Costs related to loss of production might change this in the future if the retirement age increases. Level of evidence: II Cite this article: Bone Jt Open 2021;2(12):1027–1034. The British Editorial Society of Bone & Joint Surgery 2021-12-03 /pmc/articles/PMC8711656/ /pubmed/34856811 http://dx.doi.org/10.1302/2633-1462.212.BJO-2021-0108.R1 Text en © 2021 Author(s) et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Trauma
Hassellund, Sondre
Zolic-Karlsson, Zinajda
Williksen, John Håkon
Husby, Torstein
Madsen, Jan Erik
Frihagen, Frede
Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
title Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
title_full Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
title_fullStr Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
title_full_unstemmed Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
title_short Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
title_sort surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
topic Trauma
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711656/
https://www.ncbi.nlm.nih.gov/pubmed/34856811
http://dx.doi.org/10.1302/2633-1462.212.BJO-2021-0108.R1
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