Cargando…

A Potential Participant in Type 2 Diabetes Bone Fragility: TIMP-1 at Sites of Osteocyte Lacunar-Canalicular System

Type 2 diabetes mellitus (T2DM) is associated with an increased risk of bone fracture, but the bone mineral density (BMD) is typically normal or higher in such patients. Because the fracture risk is independent of reduced BMD, bone fragility in T2DM may be partially due to poor bone quality. The mec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pei, Qilin, Li, Jun, Zhou, Pengfei, Zhang, Jun, Huang, Peng, Fan, Jingchuan, Zou, Zhen, Li, Xi, Wang, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711839/ https://www.ncbi.nlm.nih.gov/pubmed/34992398 http://dx.doi.org/10.2147/DMSO.S345081

Ejemplares similares

Glucocorticoids cause mandibular bone fragility and suppress osteocyte perilacunar-canalicular remodeling
por: Alemi, A. Sean, et al.
Publicado: (2018)

Expansion of the osteocytic lacunar-canalicular system involved in pharmacological action of PTH revealed by AI-driven fluorescence morphometry in female rabbits
por: Takakura, Aya, et al.
Publicado: (2022)

Lacunar-canalicular network in femoral cortical bone is reduced in aged women and is predominantly due to a loss of canalicular porosity
por: Ashique, A.M., et al.
Publicado: (2017)

Spatial heterogeneity in the canalicular density of the osteocyte network in human osteons
por: Repp, Felix, et al.
Publicado: (2017)

Morphometric Changes of Osteocyte Lacunar in Diabetic Pig Mandibular Cancellous Bone
por: Yao, Sheng, et al.
Publicado: (2022)

Phenomenon of osteocyte lacunar mineralization: indicator of former osteocyte death and a novel marker of impaired bone quality?
por: Milovanovic, Petar, et al.
Publicado: (2020)

Poromicromechanics reveals that physiological bone strains induce osteocyte-stimulating lacunar pressure
por: Scheiner, Stefan, et al.
Publicado: (2015)

Evidence that Osteocytes in Autogenous Bone Fragments can Repair Disrupted Canalicular Networks and Connect with Osteocytes in de novo Formed Bone on the Fragment Surface
por: Shah, Furqan A., et al.
Publicado: (2017)

Activation of HIFa Pathway in Mature Osteoblasts Disrupts the Integrity of the Osteocyte/Canalicular Network
por: Zuo, Gui-lai, et al.
Publicado: (2015)

Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis
por: Kobayashi, Keiji, et al.
Publicado: (2015)

Seeing through Musculoskeletal Tissues: Improving In Situ Imaging of Bone and the Lacunar Canalicular System through Optical Clearing
por: Berke, Ian M., et al.
Publicado: (2016)

Osteocyte lacunar strain determination using multiscale finite element analysis
por: Kola, Sravan K., et al.
Publicado: (2020)

Intraskeletal variation in human cortical osteocyte lacunar density: Implications for bone quality assessment
por: Hunter, Randee L., et al.
Publicado: (2016)

Contributions of Resin Cast Etching to Visualising the Osteocyte Lacuno-Canalicular Network Architecture in Bone Biology and Tissue Engineering
por: Sato, Mari, et al.
Publicado: (2023)

Real-Time Measurement of Solute Transport Within the Lacunar-Canalicular System of Mechanically Loaded Bone: Direct Evidence for Load-Induced Fluid Flow
por: Price, Christopher, et al.
Publicado: (2011)

Preliminary Analysis of Osteocyte Lacunar Density in Long Bones of Tetrapods: All Measures Are Bigger in Sauropod Dinosaurs
por: Stein, Koen W. H., et al.
Publicado: (2013)

Hyperglycemia compromises Rat Cortical Bone by Increasing Osteocyte Lacunar Density and Decreasing Vascular Canal Volume
por: Ay, Birol, et al.
Publicado: (2020)

Organ and tissue level properties are more sensitive to age than osteocyte lacunar characteristics in rat cortical bone
por: Wittig, Nina Kølln, et al.
Publicado: (2015)

Multifunctional Islet Transplantation Hydrogel Encapsulating A20 High-Expressing Islets
por: Bai, Xue, et al.
Publicado: (2020)

Osteohistological variation in growth marks and osteocyte lacunar density in a theropod dinosaur (Coelurosauria: Ornithomimidae)
por: Cullen, Thomas M, et al.
Publicado: (2014)

Being a binding site: Characterizing residue composition of binding sites on proteins
por: Iván, Gábor, et al.
Publicado: (2007)

Ptychographic X-ray CT characterization of the osteocyte lacuno-canalicular network in a male rat's glucocorticoid induced osteoporosis model
por: Ciani, Antonia, et al.
Publicado: (2018)

Predicted metal binding sites for phytoremediation
por: Sharma, Ashok, et al.
Publicado: (2009)

Alterations of Mass Density and 3D Osteocyte Lacunar Properties in Bisphosphonate-Related Osteonecrotic Human Jaw Bone, a Synchrotron µCT Study
por: Hesse, Bernhard, et al.
Publicado: (2014)

Outcomes of canalicular trephination versus canaliculodacryocystorhinostomy in common canalicular blocks
por: Vukkadala, Tejaswini, et al.
Publicado: (2022)

Evolutionary trace analysis at the ligand binding site of laccase
por: Mohamad, Saharuddin Bin, et al.
Publicado: (2008)

An in silico approach to map the binding site of doxorubicin on hemoglobin
por: Khan, Shahper Nazeer, et al.
Publicado: (2008)

An analysis of phosphorylation sites in protein kinases from Leishmania
por: Sinha, Sukrat, et al.
Publicado: (2016)

Go Green, Go Social: Exploring the Antecedents of Pro-Environmental Behaviors in Social Networking Sites beyond Norm Activation Theory
por: Li, Chia-Ying, et al.
Publicado: (2022)

Activation of IL-8 and its participation in cancer in schizophrenia patients: new evidence for the autoimmune hypothesis of schizophrenia
por: Xu, Lvzi, et al.
Publicado: (2018)

Lysine richness in human snurps possible sites for electrophilic attacks
por: Dey, Sanjay Kumar, et al.
Publicado: (2010)

Discovering amino acid patterns on binding sites in protein complexes
por: Kuo, Huang-Cheng, et al.
Publicado: (2011)

Detecting motifs and patterns at mobile genetic element insertion site
por: Dev, Bhuvan Bhaskar, et al.
Publicado: (2012)

Prediction of protein-mannose binding sites using random forest
por: Khare, Harshvardan, et al.
Publicado: (2012)

Occurrence of cancer at multiple sites: Towards distinguishing multigenesis from metastasis
por: Zhang, Wei-Kang, et al.
Publicado: (2008)

Binding site prediction of galanin peptide using evolutionary trace method
por: Nagarajan, Shanthi, et al.
Publicado: (2006)

Evolutionary trace analysis of plant haemoglobins: implications for site-directed mutagenesis
por: Reddy, Duvvuru muni Rajasekhara
Publicado: (2007)

Physicochemical characterization and functional site analysis of lactoferrin gene of Vechur cow
por: Shashidharan, Anisha, et al.
Publicado: (2011)

MiR-3960 binding sites with mRNA of human genes
por: Ivashchenko, Anatoly, et al.
Publicado: (2014)

Distribution of amino acids in functional sites of proteins with high melting temperature
por: Maheshwari, Amutha Selvaraj, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_npsmnijkqefmffksob6fiigj9k