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HMGB1-Induced Hepatocyte Pyroptosis Expanding Inflammatory Responses Contributes to the Pathogenesis of Acute-on-Chronic Liver Failure (ACLF)

BACKGROUND: Acute-on-chronic liver failure (ACLF) is a critical disease with a high fatality rate. Immune dysfunction and inflammatory responses are key risk factors in ACLF. Pyroptosis is a form of programmed cell death characterized by the release of inflammatory cytokines, which causes the strong...

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Detalles Bibliográficos
Autores principales:	Hou, Weixin, Wei, Xiaoyi, Liang, Jiajun, Fang, Peng, Ma, Chongyang, Zhang, Qiuyun, Gao, Yanbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711847/ https://www.ncbi.nlm.nih.gov/pubmed/34992418 http://dx.doi.org/10.2147/JIR.S336626

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