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Final Results of a Randomized, Placebo-Controlled, Two-Arm, Parallel Clinical Trial of Proxalutamide for Hospitalized COVID-19 Patients: A Multiregional, Joint Analysis of the Proxa-Rescue AndroCoV Trial
Background The role of androgens on COVID-19 is well established. Proxalutamide is a second-generation, non-steroidal antiandrogen (NSAA) with the highest antiandrogen potency among NSAAs and concurrent regulation of angiotensin-converting enzyme 2 (ACE2) expression and inflammatory response. Proxal...
Autores principales: | Cadegiani, Flavio A, Zimerman, Ricardo A, Fonseca, Daniel N, Correia, Michael N, Muller, Marcio P, Bet, Diego Leonardo, Slaviero, Marcio Rafael, Zardo, Ivan, Benites, Paulo Roberto, Barros, Renan N, Paulain, Raysa W, Onety, Dirce C, Israel, Karla Cristina P, Gustavo Wambier, Carlos, Goren, Andy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712234/ https://www.ncbi.nlm.nih.gov/pubmed/34976549 http://dx.doi.org/10.7759/cureus.20691 |
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