High Circulating Sonic Hedgehog Protein Is Associated With Poor Outcome in EGFR-Mutated Advanced NSCLC Treated With Tyrosine Kinase Inhibitors

INTRODUCTION: Growing preclinical evidence has suggested that the Sonic hedgehog (Shh) pathway is involved in resistance to tyrosine kinase inhibitor (TKI) therapy for EGFR-mutated (EGFRm) non-small cell lung cancer (NSCLC). However, little is known concerning the prognostic value of this pathway in...

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Detalles Bibliográficos
Autores principales: Takam Kamga, Paul, Swalduz, Aurélie, Costantini, Adrien, Julié, Catherine, Emile, Jean-François, Pérol, Maurice, Avrillon, Virginie, Ortiz-Cuaran, Sandra, de Saintigny, Pierre, Giroux-Leprieur, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712335/
https://www.ncbi.nlm.nih.gov/pubmed/34970481
http://dx.doi.org/10.3389/fonc.2021.747692

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