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Hierarchical Regulation of the Resting and Activated T Cell Epigenome by Major Transcription Factor Families
T cell activation, a key early event in the adaptive immune response, is subject to elaborate transcriptional control. Here, we examined how the activities of eight major transcription factor (TF) families are integrated to shape the epigenome of naïve and activated CD4 and CD8 T cells. By leveragin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712421/ https://www.ncbi.nlm.nih.gov/pubmed/34937932 http://dx.doi.org/10.1038/s41590-021-01086-x |