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Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network
Clinically, red blood cell abnormalities are closely related to tumor diseases, red blood cell diseases, internal medicine, and other diseases. Red blood cell classification is the key to detecting red blood cell abnormalities. Traditional red blood cell classification is done manually by doctors, w...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712440/ https://www.ncbi.nlm.nih.gov/pubmed/34970557 http://dx.doi.org/10.3389/fmed.2021.741407 |
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author | Song, Weiqing Huang, Pu Wang, Jing Shen, Yajuan Zhang, Jian Lu, Zhiming Li, Dengwang Liu, Danhua |
author_facet | Song, Weiqing Huang, Pu Wang, Jing Shen, Yajuan Zhang, Jian Lu, Zhiming Li, Dengwang Liu, Danhua |
author_sort | Song, Weiqing |
collection | PubMed |
description | Clinically, red blood cell abnormalities are closely related to tumor diseases, red blood cell diseases, internal medicine, and other diseases. Red blood cell classification is the key to detecting red blood cell abnormalities. Traditional red blood cell classification is done manually by doctors, which requires a lot of manpower produces subjective results. This paper proposes an Attention-based Residual Feature Pyramid Network (ARFPN) to classify 14 types of red blood cells to assist the diagnosis of related diseases. The model performs classification directly on the entire red blood cell image. Meanwhile, a spatial attention mechanism and channel attention mechanism are combined with residual units to improve the expression of category-related features and achieve accurate extraction of features. Besides, the RoI align method is used to reduce the loss of spatial symmetry and improve classification accuracy. Five hundred and eighty eight red blood cell images are used to train and verify the effectiveness of the proposed method. The Channel Attention Residual Feature Pyramid Network (C-ARFPN) model achieves an mAP of 86%; the Channel and Spatial Attention Residual Feature Pyramid Network (CS-ARFPN) model achieves an mAP of 86.9%. The experimental results indicate that our method can classify more red blood cell types and better adapt to the needs of doctors, thus reducing the doctor's time and improving the diagnosis efficiency. |
format | Online Article Text |
id | pubmed-8712440 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87124402021-12-29 Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network Song, Weiqing Huang, Pu Wang, Jing Shen, Yajuan Zhang, Jian Lu, Zhiming Li, Dengwang Liu, Danhua Front Med (Lausanne) Medicine Clinically, red blood cell abnormalities are closely related to tumor diseases, red blood cell diseases, internal medicine, and other diseases. Red blood cell classification is the key to detecting red blood cell abnormalities. Traditional red blood cell classification is done manually by doctors, which requires a lot of manpower produces subjective results. This paper proposes an Attention-based Residual Feature Pyramid Network (ARFPN) to classify 14 types of red blood cells to assist the diagnosis of related diseases. The model performs classification directly on the entire red blood cell image. Meanwhile, a spatial attention mechanism and channel attention mechanism are combined with residual units to improve the expression of category-related features and achieve accurate extraction of features. Besides, the RoI align method is used to reduce the loss of spatial symmetry and improve classification accuracy. Five hundred and eighty eight red blood cell images are used to train and verify the effectiveness of the proposed method. The Channel Attention Residual Feature Pyramid Network (C-ARFPN) model achieves an mAP of 86%; the Channel and Spatial Attention Residual Feature Pyramid Network (CS-ARFPN) model achieves an mAP of 86.9%. The experimental results indicate that our method can classify more red blood cell types and better adapt to the needs of doctors, thus reducing the doctor's time and improving the diagnosis efficiency. Frontiers Media S.A. 2021-12-14 /pmc/articles/PMC8712440/ /pubmed/34970557 http://dx.doi.org/10.3389/fmed.2021.741407 Text en Copyright © 2021 Song, Huang, Wang, Shen, Zhang, Lu, Li and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Song, Weiqing Huang, Pu Wang, Jing Shen, Yajuan Zhang, Jian Lu, Zhiming Li, Dengwang Liu, Danhua Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network |
title | Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network |
title_full | Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network |
title_fullStr | Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network |
title_full_unstemmed | Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network |
title_short | Red Blood Cell Classification Based on Attention Residual Feature Pyramid Network |
title_sort | red blood cell classification based on attention residual feature pyramid network |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712440/ https://www.ncbi.nlm.nih.gov/pubmed/34970557 http://dx.doi.org/10.3389/fmed.2021.741407 |
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