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Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions

NK cells are contained in the ILC1 group; they are recognized for their antiviral and antitumor cytotoxic capacity; NK cells also participate in other immune response processes through cytokines secretion. However, the mechanisms that regulate these functions are poorly understood since NK cells are...

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Autores principales: Cruz-Zárate, David, Miguel-Rodríguez, Carlos Emilio, Martínez-Vargas, Irving Ulises, Santos-Argumedo, Leopoldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712487/
https://www.ncbi.nlm.nih.gov/pubmed/34970258
http://dx.doi.org/10.3389/fimmu.2021.760290
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author Cruz-Zárate, David
Miguel-Rodríguez, Carlos Emilio
Martínez-Vargas, Irving Ulises
Santos-Argumedo, Leopoldo
author_facet Cruz-Zárate, David
Miguel-Rodríguez, Carlos Emilio
Martínez-Vargas, Irving Ulises
Santos-Argumedo, Leopoldo
author_sort Cruz-Zárate, David
collection PubMed
description NK cells are contained in the ILC1 group; they are recognized for their antiviral and antitumor cytotoxic capacity; NK cells also participate in other immune response processes through cytokines secretion. However, the mechanisms that regulate these functions are poorly understood since NK cells are not as abundant as other lymphocytes, which has made them difficult to study. Using public databases, we identified that NK cells express mRNA encoding class I myosins, among which Myosin 1g and Myosin 1f are prominent. Therefore, this mini-review aims to generate a model of the probable participation of Myosin 1g and 1f in NK cells, based on information reported about the function of these myosins in other leukocytes.
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spelling pubmed-87124872021-12-29 Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions Cruz-Zárate, David Miguel-Rodríguez, Carlos Emilio Martínez-Vargas, Irving Ulises Santos-Argumedo, Leopoldo Front Immunol Immunology NK cells are contained in the ILC1 group; they are recognized for their antiviral and antitumor cytotoxic capacity; NK cells also participate in other immune response processes through cytokines secretion. However, the mechanisms that regulate these functions are poorly understood since NK cells are not as abundant as other lymphocytes, which has made them difficult to study. Using public databases, we identified that NK cells express mRNA encoding class I myosins, among which Myosin 1g and Myosin 1f are prominent. Therefore, this mini-review aims to generate a model of the probable participation of Myosin 1g and 1f in NK cells, based on information reported about the function of these myosins in other leukocytes. Frontiers Media S.A. 2021-12-14 /pmc/articles/PMC8712487/ /pubmed/34970258 http://dx.doi.org/10.3389/fimmu.2021.760290 Text en Copyright © 2021 Cruz-Zárate, Miguel-Rodríguez, Martínez-Vargas and Santos-Argumedo https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Cruz-Zárate, David
Miguel-Rodríguez, Carlos Emilio
Martínez-Vargas, Irving Ulises
Santos-Argumedo, Leopoldo
Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
title Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
title_full Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
title_fullStr Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
title_full_unstemmed Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
title_short Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
title_sort myosin 1g and 1f: a prospective analysis in nk cell functions
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712487/
https://www.ncbi.nlm.nih.gov/pubmed/34970258
http://dx.doi.org/10.3389/fimmu.2021.760290
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