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Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
NK cells are contained in the ILC1 group; they are recognized for their antiviral and antitumor cytotoxic capacity; NK cells also participate in other immune response processes through cytokines secretion. However, the mechanisms that regulate these functions are poorly understood since NK cells are...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712487/ https://www.ncbi.nlm.nih.gov/pubmed/34970258 http://dx.doi.org/10.3389/fimmu.2021.760290 |
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author | Cruz-Zárate, David Miguel-Rodríguez, Carlos Emilio Martínez-Vargas, Irving Ulises Santos-Argumedo, Leopoldo |
author_facet | Cruz-Zárate, David Miguel-Rodríguez, Carlos Emilio Martínez-Vargas, Irving Ulises Santos-Argumedo, Leopoldo |
author_sort | Cruz-Zárate, David |
collection | PubMed |
description | NK cells are contained in the ILC1 group; they are recognized for their antiviral and antitumor cytotoxic capacity; NK cells also participate in other immune response processes through cytokines secretion. However, the mechanisms that regulate these functions are poorly understood since NK cells are not as abundant as other lymphocytes, which has made them difficult to study. Using public databases, we identified that NK cells express mRNA encoding class I myosins, among which Myosin 1g and Myosin 1f are prominent. Therefore, this mini-review aims to generate a model of the probable participation of Myosin 1g and 1f in NK cells, based on information reported about the function of these myosins in other leukocytes. |
format | Online Article Text |
id | pubmed-8712487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87124872021-12-29 Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions Cruz-Zárate, David Miguel-Rodríguez, Carlos Emilio Martínez-Vargas, Irving Ulises Santos-Argumedo, Leopoldo Front Immunol Immunology NK cells are contained in the ILC1 group; they are recognized for their antiviral and antitumor cytotoxic capacity; NK cells also participate in other immune response processes through cytokines secretion. However, the mechanisms that regulate these functions are poorly understood since NK cells are not as abundant as other lymphocytes, which has made them difficult to study. Using public databases, we identified that NK cells express mRNA encoding class I myosins, among which Myosin 1g and Myosin 1f are prominent. Therefore, this mini-review aims to generate a model of the probable participation of Myosin 1g and 1f in NK cells, based on information reported about the function of these myosins in other leukocytes. Frontiers Media S.A. 2021-12-14 /pmc/articles/PMC8712487/ /pubmed/34970258 http://dx.doi.org/10.3389/fimmu.2021.760290 Text en Copyright © 2021 Cruz-Zárate, Miguel-Rodríguez, Martínez-Vargas and Santos-Argumedo https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Cruz-Zárate, David Miguel-Rodríguez, Carlos Emilio Martínez-Vargas, Irving Ulises Santos-Argumedo, Leopoldo Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions |
title | Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions |
title_full | Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions |
title_fullStr | Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions |
title_full_unstemmed | Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions |
title_short | Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions |
title_sort | myosin 1g and 1f: a prospective analysis in nk cell functions |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712487/ https://www.ncbi.nlm.nih.gov/pubmed/34970258 http://dx.doi.org/10.3389/fimmu.2021.760290 |
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