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Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2
Histone lysine crotonylation is a posttranslational modification with demonstrated functions in transcriptional regulation. Here we report the discovery of a new type of histone posttranslational modification, lysine methacrylation (Kmea), corresponding to a structural isomer of crotonyllysine. We v...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712513/ https://www.ncbi.nlm.nih.gov/pubmed/34961760 http://dx.doi.org/10.1038/s41421-021-00344-4 |