Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2

Histone lysine crotonylation is a posttranslational modification with demonstrated functions in transcriptional regulation. Here we report the discovery of a new type of histone posttranslational modification, lysine methacrylation (Kmea), corresponding to a structural isomer of crotonyllysine. We v...

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Detalles Bibliográficos
Autores principales: Delaney, Kyle, Tan, Minjia, Zhu, Zhesi, Gao, Jinjun, Dai, Lunzhi, Kim, Sunjoo, Ding, Jun, He, Maomao, Halabelian, Levon, Yang, Lu, Nagarajan, Prabakaran, Parthun, Mark Robert, Lee, Sangkyu, Khochbin, Saadi, Zheng, Yujun George, Zhao, Yingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712513/
https://www.ncbi.nlm.nih.gov/pubmed/34961760
http://dx.doi.org/10.1038/s41421-021-00344-4

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