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Kinetic control of nascent protein biogenesis by peptide deformylase

Synthesis of bacterial proteins on the ribosome starts with a formylated methionine. Removal of the N-terminal formyl group is essential and is carried out by peptide deformylase (PDF). Deformylation occurs co-translationally, shortly after the nascent-chain emerges from the ribosomal exit tunnel, a...

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Detalles Bibliográficos
Autores principales: Bögeholz, Lena A. K., Mercier, Evan, Wintermeyer, Wolfgang, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712518/
https://www.ncbi.nlm.nih.gov/pubmed/34961771
http://dx.doi.org/10.1038/s41598-021-03969-3

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