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Kinetic control of nascent protein biogenesis by peptide deformylase
Synthesis of bacterial proteins on the ribosome starts with a formylated methionine. Removal of the N-terminal formyl group is essential and is carried out by peptide deformylase (PDF). Deformylation occurs co-translationally, shortly after the nascent-chain emerges from the ribosomal exit tunnel, a...
Autores principales: | Bögeholz, Lena A. K., Mercier, Evan, Wintermeyer, Wolfgang, Rodnina, Marina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712518/ https://www.ncbi.nlm.nih.gov/pubmed/34961771 http://dx.doi.org/10.1038/s41598-021-03969-3 |
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