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Ilexsaponin A(1) Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice

Bile acid (BA) metabolism is an attractive therapeutic target in nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the effect of ilexsaponin A(1) (IsA), a major bioactive ingredient of Ilex, on high-fat diet (HFD)-induced NAFLD in mice with a focus on BA homeostasis. Male C57BL/6J mi...

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Detalles Bibliográficos
Autores principales:	Zhao, Wen-wen, Xiao, Meng, Wu, Xia, Li, Xiu-wei, Li, Xiao-xi, Zhao, Ting, Yu, Lan, Chen, Xiao-qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712733/ https://www.ncbi.nlm.nih.gov/pubmed/34970143 http://dx.doi.org/10.3389/fphar.2021.771976

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